AlphaPulldown2—a general pipeline for high-throughput structural modeling
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Summary
AlphaPulldown2 streamlines protein structural modeling by automating workflows, improving code adaptability, and optimizing data management for large-scale applications. It introduces an automated Snakemake pipeline, compressed data storage, support for additional modeling backends like UniFold and AlphaLink2, and a range of other improvements. These upgrades make AlphaPulldown2 a versatile platform for predicting both binary interactions and complex multi-unit assemblies.
Availability and implementation
AlphaPulldown2 is freely available at https://github.com/KosinskiLab/AlphaPulldown.
