Co-circulation of Clade Ia and Ib monkeypox virus in Kinshasa Province, Democratic Republic of the Congo, July - August 2024

  1. Tony Wawina-Bokalanga
  2. Prince Akil-Bandali
  3. Eddy Kinganda-Lusamaki
  4. Emmanuel Lokilo
  5. Daan Jansen
  6. Adrienne Amuri-Aziza
  7. Jean-Claude Makangara-Cigolo
  8. Elisabeth Pukuta-Simbu
  9. Rilia Ola-Mpumbe
  10. Cris Kacita
  11. Princesse Paku-Tshambu
  12. Pedro-Henrique L.F. Dantas
  13. Gradi Luakanda
  14. Antoine Nkuba-Ndaye
  15. Meris Matondo
  16. Junior Bulabula
  17. Emmanuel Hasivirwe Vakaniaki
  18. Áine O’Toole
  19. Tessa De Block
  20. Christian Ngandu
  21. Nicole A. Hoff
  22. Nicola Low
  23. Lorenzo Subissi
  24. Sydney Merritt
  25. Jean-Jacques Muyembe-Tamfum
  26. Laurens Liesenborghs
  27. Martine Peeters
  28. Eric Delaporte
  29. Jason Kindrachuk
  30. Anne W. Rimoin
  31. Steve Ahuka-Mundeke
  32. Andrew Rambaut
  33. Dieudonné Mwamba
  34. Koen Vercauteren
  35. Placide Mbala-Kingebeni
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Abstract

Mpox cases have been reported in nearly all provinces of the Democratic Republic of the Congo as of August 2024. Monkeypox virus positive samples from Kinshasa, collected between July and mid-August 2024, were sequenced using a probe-based enrichment or optimized tiling sequencing protocol. With multiple introductions of both Clade Ia (7/12) and Ib (5/12), marking Kinshasa, and its Limete health zone specifically, as an area with co-circulation of both Clade I, a unique observation illustrating the growing complexity of Clade I mpox outbreaks in DRC.

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  1. Version published to 10.1101/2024.09.03.24312937v1 on medRxiv