Clade I mpox virus genomic diversity in the Democratic Republic of the Congo, 2018–2024: Predominance of zoonotic transmission

  1. Eddy Kinganda-Lusamaki
  2. Adrienne Amuri-Aziza
  3. Nicolas Fernandez-Nuñez
  4. Jean-Claude Makangara-Cigolo
  5. Catherine Pratt
  6. Emmanuel Hasivirwe Vakaniaki
  7. Nicole A. Hoff
  8. Gradi Luakanda-Ndelemo
  9. Prince Akil-Bandali
  10. Sabin Sabiti Nundu
  11. Noella Mulopo-Mukanya
  12. Michel Ngimba
  13. Brigitte Modadra-Madakpa
  14. Ruth Diavita
  15. Princesse Paku-Tshambu
  16. Elisabeth Pukuta-Simbu
  17. Sydney Merritt
  18. Áine O’Toole
  19. Nicola Low
  20. Antoine Nkuba-Ndaye
  21. Hugo Kavunga-Membo
  22. Robert Shongo Lushima
  23. Laurens Liesenborghs
  24. Tony Wawina-Bokalanga
  25. Koen Vercauteren
  26. Daniel Mukadi-Bamuleka
  27. Lorenzo Subissi
  28. Jean-Jacques Muyembe-Tamfum
  29. Jason Kindrachuk
  30. Ahidjo Ayouba
  31. Andrew Rambaut
  32. Eric Delaporte
  33. Sofonias Tessema
  34. Eric D’Ortenzio
  35. Anne W. Rimoin
  36. Lisa E. Hensley
  37. Placide Mbala-Kingebeni
  38. Martine Peeters
  39. Steve Ahuka-Mundeke

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Abstract

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  1. Version published to 10.1016/j.cell.2024.10.017
  2. Rapid Reviews Infectious Diseases

    Safdar Ali

    Review 6: "Clade I Mpox Virus Genomic Diversity in the Democratic Republic of the Congo, 2018 - 2024: Predominance of Zoonotic Transmission"

    Overall, the reviewers appreciated the authors' candid acknowledgment of the study's limitations, including potential sampling biases, and recognized the urgent need for enhanced genomic surveillance to mitigate the mpox epidemic in the DRC. 

  3. Rapid Reviews Infectious Diseases

    Utpal S Tatu, Ankeet Kumar

    Review 5: "Clade I Mpox Virus Genomic Diversity in the Democratic Republic of the Congo, 2018 - 2024: Predominance of Zoonotic Transmission"

    Overall, the reviewers appreciated the authors' candid acknowledgment of the study's limitations, including potential sampling biases, and recognized the urgent need for enhanced genomic surveillance to mitigate the mpox epidemic in the DRC. 

  4. Rapid Reviews Infectious Diseases

    Roshan Kumar

    Review 4: "Clade I Mpox Virus Genomic Diversity in the Democratic Republic of the Congo, 2018 - 2024: Predominance of Zoonotic Transmission"

    Overall, the reviewers appreciated the authors' candid acknowledgment of the study's limitations, including potential sampling biases, and recognized the urgent need for enhanced genomic surveillance to mitigate the mpox epidemic in the DRC. 

  5. Rapid Reviews Infectious Diseases

    Jian Lu

    Review 3: "Clade I Mpox Virus Genomic Diversity in the Democratic Republic of the Congo, 2018 - 2024: Predominance of Zoonotic Transmission"

    Overall, the reviewers appreciated the authors' candid acknowledgment of the study's limitations, including potential sampling biases, and recognized the urgent need for enhanced genomic surveillance to mitigate the mpox epidemic in the DRC. 

  6. Rapid Reviews Infectious Diseases

    Chantal Vogels

    Review 2: "Clade I Mpox Virus Genomic Diversity in the Democratic Republic of the Congo, 2018 - 2024: Predominance of Zoonotic Transmission"

    Overall, the reviewers appreciated the authors' candid acknowledgment of the study's limitations, including potential sampling biases, and recognized the urgent need for enhanced genomic surveillance to mitigate the mpox epidemic in the DRC. 

  7. Rapid Reviews Infectious Diseases

    Jingzhe Shang

    Review 1: "Clade I Mpox Virus Genomic Diversity in the Democratic Republic of the Congo, 2018 - 2024: Predominance of Zoonotic Transmission"

    Overall, the reviewers appreciated the authors' candid acknowledgment of the study's limitations, including potential sampling biases, and recognized the urgent need for enhanced genomic surveillance to mitigate the mpox epidemic in the DRC. 

  8. Rapid Reviews Infectious Diseases

    Strength of evidence

    Reviewers: J Shang (Suzhou Inst. of Systems Medicine) |📘📘📘📘📘
    C Vogles (Yale) |📘📘📘📘📘
    J Lu (Peking University) |📗📗📗📗◻️
    R Kumar (Magadh University) |📗📗📗📗◻️
    U Tatu & A Kumar (Indian Institute of Science) |📒📒📒 ◻️◻️
    S Ali (Aliah University) |📘📘📘📘📘

  9. Version published to 10.1101/2024.08.13.24311951v2 on medRxiv
  10. Version published to 10.1101/2024.08.13.24311951v1 on medRxiv