Conservation of animal genome structure is the exception not the rule
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Species from diverse animal lineages have retained groups of orthologous genes together on the same chromosomes for over half a billion years since their last common ancestor. However, by examining interchromosomal rearrangements across all major bilaterian groups, we show that cases of high-fidelity genome structure conservation are unexpectedly rare. Large-scale genome restructuring events are pervasive, correlate with increased rates of protein sequence evolution, and may contribute to adaptation and animal diversity.
