Flynotyper 2.0: A tool for rapid quantitative assessment of Drosophila eye phenotypes
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About two-thirds of the genes in the Drosophila melanogaster genome is also involved in its eye development, making the Drosophila eye an ideal tool for genetic studies. We developed Flynotyper that uses image processing operations to identify and quantify the degree of roughness by measuring disorderliness of ommatidial arrangement in the fly eye. This software has enabled researchers to quantify morphological defects of thousands of eye images caused by genetic perturbations. Here, we updated Flynotyper’s computer vision library, improved its performance, and streamlined the analysis for high-throughput analysis of multiple eye images. We also tested several batches of Drosophila eye images to ensure robustness and reproducibility of the updated Flynotyper software.
Availability and implementation
The source code for Flynotyper 2.0 can be downloaded and installed from https://github.com/girirajanlab/flynotyper-desktop-application .
