COGNITIVE ASSESSMENT WITH COGNIVUE CLARITY ® : PSYCHOMETRIC PROPERTIES AND ENHANCED NORMATIVE RANGES IN A DIVERSE POPULATION
Listed in
This article is not in any list yet, why not save it to one of your lists.Abstract
Background
Detecting cognitive impairment in clinical practice is challenging as most instruments do not perform well in diverse samples of older adults. These same instruments are often used for eligibility into clinical trials making it difficult to recruit minoritized adults into Alzheimer’s disease (AD) studies. Cognivue Clarity ® is an FDA-cleared computerized cognitive screening platform using adaptive psychophysics to detect cognitive impairment.
Objective
Test the ability of Cognivue Clarity to detect cognitive impairment in a diverse community sample compared with the Repeatable Battery for the Assessment of Neuropsychological Status (RBANS).
Methods
This study enrolled 452 participants across 6 US study sites and completed both Cognivue Clarity device and RBANS. Psychometric properties and exploratory factor analysis of Cognivue Clarity were explored and comparisons against RBANS across different age, sex, education, and ethnoracial groups were conducted.
Results
Participants had a mean age of 47.9±16.1 years (range: 18-85), 63.6% were female, 45.9% had < 12 years of education, 31.2% were African American and 9.2% were Hispanic. Cognivue Clarity had strong internal consistency, test-retest and minimal practice effects. A 4-factor structure (Memory, Attention, Visuomotor, and Discrimination) had excellent goodness of fit. Normalizing age effects improved performance. Race and education effects were similar to those seen with RBANS. Cognivue Clarity had strong correlation with RBANS.
Conclusions
Our study supports the use of Cognivue Clarity as an easy-to-use, brief, and valid cognitive assessment that can be used for identifying individuals with likely cognitive impairment in the clinical setting and those who could be candidates for AD research studies.
