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  1. SciScore for 10.1101/2022.06.02.494502: (What is this?)

    Please note, not all rigor criteria are appropriate for all manuscripts.

    Table 1: Rigor

    EthicsIACUC: All the experimental protocols were approved by Institutional Animal Care and Use Committee.
    Sex as a biological variableImmunization experiments: Adult (6 to 8 weeks old) females Balb/c mice (inbred, H-2d) were housed at Beijing Vital River Laboratory Animal Technology Co
    RandomizationSamples (three or five mice per group) were processed individualized, with the exception of the control groups (Placebos) which were processed as pooled samples of three randomly selected mice.
    Blindingnot detected.
    Power Analysisnot detected.

    Table 2: Resources

    Antibodies
    SentencesResources
    Assessment of cellular immune response by IFN-γ ELISPOT: IFN-γ ELISPOT assay was performed using a Mouse IFN-γ ELISpot antibody pair (Mabtech, Sweden).
    IFN-γ
    suggested: None
    Experimental Models: Organisms/Strains
    SentencesResources
    Immunization experiments: Adult (6 to 8 weeks old) females Balb/c mice (inbred, H-2d) were housed at Beijing Vital River Laboratory Animal Technology Co
    Balb/c
    suggested: RRID:IMSR_ORNL:BALB/cRl)
    Software and Algorithms
    SentencesResources
    Statistical analysis: For statistical analyses the GraphPad Prism version 5.00 statistical software (
    GraphPad
    suggested: (GraphPad Prism, RRID:SCR_002798)

    Results from OddPub: We did not detect open data. We also did not detect open code. Researchers are encouraged to share open data when possible (see Nature blog).


    Results from LimitationRecognizer: An explicit section about the limitations of the techniques employed in this study was not found. We encourage authors to address study limitations.

    Results from TrialIdentifier: No clinical trial numbers were referenced.


    Results from Barzooka: We did not find any issues relating to the usage of bar graphs.


    Results from JetFighter: We did not find any issues relating to colormaps.


    Results from rtransparent:
    • Thank you for including a conflict of interest statement. Authors are encouraged to include this statement when submitting to a journal.
    • Thank you for including a funding statement. Authors are encouraged to include this statement when submitting to a journal.
    • No protocol registration statement was detected.

    Results from scite Reference Check: We found no unreliable references.


    About SciScore

    SciScore is an automated tool that is designed to assist expert reviewers by finding and presenting formulaic information scattered throughout a paper in a standard, easy to digest format. SciScore checks for the presence and correctness of RRIDs (research resource identifiers), and for rigor criteria such as sex and investigator blinding. For details on the theoretical underpinning of rigor criteria and the tools shown here, including references cited, please follow this link.

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