CHARACTERISTICS AND OUTCOMES OF INDIVIDUALS WITH COVID-19: EVIDENCE FROM A HOSPITAL BASED STUDY

  1. P. Simushi
  2. M. Zambwe
  3. P.J. Chipimo

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Abstract

Objective

To determine the characteristics and outcomes of Covid-19 patients at Livingstone teaching hospital.

Methods

A database cross sectional review of COVID 19 patients at Livingstone Teaching Hospital. Data on demographics and clinical characteristics were obtained along with the comorbidities presented with by the patients using a structured data collection form. Data were analysed using STATA 64. Mann-Whitney and t-test were used on continuous independent variables. Chi-square test was used to determine associations between two categorical variables. Logistic regression was used to control for confounders.

Results

A total of 222 (62.54%) were male and 133 (37.46%) were female. Discharged were 274 (77.18%), while 81 (22.82%) died. Among those who died were the older clients with a median age of 65 (p <0.001). The median interquartile range (IQR)] age was 48.5 years. Patients presented with a cough 180 (50.7%), chest pain 123 (34.65%) and shortness of breath 121 (34.04%). Statistically significant comorbidities recorded included Hypertension 121 (34.08%), Diabetes mellitus 69 (19.44%), and HIV 38 (10.7%). The most prevalent underlying condition observed was hypertension 121 (34.08).

Conclusion

HIV positive and diabetics had an increased odds of succumbing to COVID-19 death. It is recommended that targeted policies should be considered the risky groups.

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    SciScore for 10.1101/2022.05.13.22274812: (What is this?)

    Please note, not all rigor criteria are appropriate for all manuscripts.

    Table 1: Rigor

    EthicsField Sample Permit: We conducted a census of all patients admitted at Livingstone Teaching Hospital after permission had been granted by the University of Lusaka, School of Medicine & Health Sciences Research Ethics Committee, the National Health Research Authority (NHRA) and Mulungushi University School of Medicine and Health Sciences research ethics committee (MUSoMHS-REC).
    IRB: We conducted a census of all patients admitted at Livingstone Teaching Hospital after permission had been granted by the University of Lusaka, School of Medicine & Health Sciences Research Ethics Committee, the National Health Research Authority (NHRA) and Mulungushi University School of Medicine and Health Sciences research ethics committee (MUSoMHS-REC).
    Sex as a biological variablenot detected.
    Randomizationnot detected.
    Blindingnot detected.
    Power Analysisnot detected.

    Table 2: Resources

    Software and Algorithms
    SentencesResources
    Data was analysed using STATA 64 to produce descriptive statistics.
    STATA
    suggested: (Stata, RRID:SCR_012763)

    Results from OddPub: We did not detect open data. We also did not detect open code. Researchers are encouraged to share open data when possible (see Nature blog).

    Results from LimitationRecognizer: An explicit section about the limitations of the techniques employed in this study was not found. We encourage authors to address study limitations.

    Results from TrialIdentifier: No clinical trial numbers were referenced.

    Results from Barzooka: We did not find any issues relating to the usage of bar graphs.

    Results from JetFighter: We did not find any issues relating to colormaps.

    Results from rtransparent:
    • Thank you for including a conflict of interest statement. Authors are encouraged to include this statement when submitting to a journal.
    • Thank you for including a funding statement. Authors are encouraged to include this statement when submitting to a journal.
    • No protocol registration statement was detected.

    Results from scite Reference Check: We found no unreliable references.

    About SciScore

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  2. Version published to 10.1101/2022.05.13.22274812v1 on medRxiv