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  1. SciScore for 10.1101/2022.05.06.490883: (What is this?)

    Please note, not all rigor criteria are appropriate for all manuscripts.

    Table 1: Rigor

    Ethicsnot detected.
    Sex as a biological variablenot detected.
    Randomizationnot detected.
    Blindingnot detected.
    Power Analysisnot detected.

    Table 2: Resources

    No key resources detected.

    Results from OddPub: Thank you for sharing your data.

    Results from LimitationRecognizer: We detected the following sentences addressing limitations in the study:
    4.1 Limitations of this study: The presented model has several limitations: (1) we assume only a single immune cell population, with only a single phenotype; (2) we assume that macrophages may only activate via a single (classical) route; (3) healthy epithelial cells and resting macrophages do not produce cytokines; (4) only a limited set of cytokines is considered; and finally (5) there is a fair amount of uncertainty surrounding the parameter values. Mathematical and computational models require initial simplification, as well as subsequent iterative development, but can never-the-less, offer a unique perspective that can help enhance understanding. Therefore, the presented model serves as an initial starting point from which we can build, by including further complexity and more detailed study which can inform or enhance experimental studies.

    Results from TrialIdentifier: No clinical trial numbers were referenced.

    Results from Barzooka: We did not find any issues relating to the usage of bar graphs.

    Results from JetFighter: We did not find any issues relating to colormaps.

    Results from rtransparent:
    • Thank you for including a conflict of interest statement. Authors are encouraged to include this statement when submitting to a journal.
    • Thank you for including a funding statement. Authors are encouraged to include this statement when submitting to a journal.
    • No protocol registration statement was detected.

    Results from scite Reference Check: We found no unreliable references.

    About SciScore

    SciScore is an automated tool that is designed to assist expert reviewers by finding and presenting formulaic information scattered throughout a paper in a standard, easy to digest format. SciScore checks for the presence and correctness of RRIDs (research resource identifiers), and for rigor criteria such as sex and investigator blinding. For details on the theoretical underpinning of rigor criteria and the tools shown here, including references cited, please follow this link.

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