Role of Covid vaccine in determining ICU admission and death due to Covid-19 in Tamil Nadu

  1. T S Selvavinayagam
  2. K Parthipan
  3. Sudharshini Subramaniam
  4. A Somasundaram
  5. P Sampath
  6. Vinay Kumar

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Abstract

COVID-19 pandemic threatened the world in terms of its rapid spread, strain on health infrastructure and many people lost their lives due to COVID. Mass Vaccination of public against Covid-19 were done with the notion that it protects against the severe form of the disease and death due to Covid-19. Covid vaccination was rolled out in Tamil Nadu from 16 th January 2021 in a phased manner. This study was done using secondary data to assess the role of COVID vaccination in preventing ICU admission and death due to Covid-19 in Tamil Nadu for the period of August – December 2021. Unvaccinated individuals contributed to a higher proportion of hospitalization (60.9%) and ICU admission (65.5%) among Covid-19 infected during this period. Similarly, among patients who died due to Covid-19, 75.5% were unvaccinated. Odds of ICU admission and death among unvaccinated was 2.01 and 3.19 - times higher compared to fully vaccinated individuals infected with Covid-19. Unvaccinated Covid-19 patients had 2.73- and 1.46- times increased odds of dying and ICU admission respectively, compared to partially vaccinated. Population Attributable Risk showed that receiving at least one dose of vaccine could have reduced the mortality among Covid patients by 54% and ICU admission by 23.3%. This article emphasizes the need for vaccination against Covid-19 to reduce ICU admission and death among those infected with Covid-19.

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  1. ScreenIT

    SciScore for 10.1101/2022.02.07.22270596: (What is this?)

    Please note, not all rigor criteria are appropriate for all manuscripts.

    Table 1: Rigor

    Ethicsnot detected.
    Sex as a biological variablenot detected.
    Randomizationnot detected.
    Blindingnot detected.
    Power Analysisnot detected.

    Table 2: Resources

    No key resources detected.

    Results from OddPub: We did not detect open data. We also did not detect open code. Researchers are encouraged to share open data when possible (see Nature blog).

    Results from LimitationRecognizer: An explicit section about the limitations of the techniques employed in this study was not found. We encourage authors to address study limitations.

    Results from TrialIdentifier: No clinical trial numbers were referenced.

    Results from Barzooka: We did not find any issues relating to the usage of bar graphs.

    Results from JetFighter: We did not find any issues relating to colormaps.

    Results from rtransparent:
    • Thank you for including a conflict of interest statement. Authors are encouraged to include this statement when submitting to a journal.
    • Thank you for including a funding statement. Authors are encouraged to include this statement when submitting to a journal.
    • No protocol registration statement was detected.

    Results from scite Reference Check: We found no unreliable references.

    About SciScore

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  2. Version published to 10.1101/2022.02.07.22270596 on medRxiv