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  1. SciScore for 10.1101/2022.01.18.22269501: (What is this?)

    Please note, not all rigor criteria are appropriate for all manuscripts.

    Table 1: Rigor

    EthicsIRB: Ethical statement: Usage of human sera from participants of age older than 18 received approval from the Mahidol University Central Institutional Review Board (MU-CIRB) under protocol number MU-COVID2020.001/2503.
    Consent: In the enrollment process for participants in groups 2 and 3, epidemiologists explained the purpose of the study to obtain written consent for interviewing about their demographics, occupation, workplace, residence, and general health condition, including a donation of 5-8 ml of blood, with specimens labeled using ID codes. 4) Thai citizens in state quarantines, when arrived Thailand after extended duties in countries with known SARS-CoV-2 outbreaks.
    Sex as a biological variablenot detected.
    Randomizationnot detected.
    Blindingnot detected.
    Power Analysisnot detected.
    Cell Line Authenticationnot detected.

    Table 2: Resources

    Blood specimens were collected for anti-SARS-CoV-2 antibody testing [along with real-time reverse transcription-polymerase chain reaction (RT-PCR)] to support active case surveillance activities conducted by the Institute for Urban Disease Control and Prevention (IUDC), DDC, MoPH.
    suggested: None
    When results of the two assays were concordant, the test serum was considered positive or negative for anti-SARS antibodies.
    suggested: None
    A titer of 10 or greater was considered positive for NT antibody.
    suggested: None
    Experimental Models: Cell Lines
    The assay employed SARS-CoV-2-infected Vero cells deposited on microscopic slides as the test antigens.
    suggested: CLS Cat# 605372/p622_VERO, RRID:CVCL_0059)
    Software and Algorithms
    Chemiluminescence immunoassay: CLIA using Architect auto-analyzer (Abbott Laboratories, USA) is the two-step, fully automated immunoassay that qualitatively detected binding between the SARS-CoV-2 nucleoprotein (N) antigen coated on paramagnetic microparticles and human IgG in the test sera.
    Abbott Laboratories
    suggested: None
    Statistical analysis: R square (R2), mean, and standard deviation (SD) were determined, and figures were drawn using GraphPad Prism version 8.4.3 for Windows (GraphPad Software, La Jolla, California, USA).
    GraphPad Prism
    suggested: (GraphPad Prism, RRID:SCR_002798)
    suggested: (GraphPad Prism, RRID:SCR_002798)
    The McNemar test was carried out and 95% confidence interval (95% CI) calculated by SPSS Statistic software version 18.0.
    suggested: (SPSS, RRID:SCR_002865)

    Results from OddPub: We did not detect open data. We also did not detect open code. Researchers are encouraged to share open data when possible (see Nature blog).

    Results from LimitationRecognizer: An explicit section about the limitations of the techniques employed in this study was not found. We encourage authors to address study limitations.

    Results from TrialIdentifier: No clinical trial numbers were referenced.

    Results from Barzooka: We did not find any issues relating to the usage of bar graphs.

    Results from JetFighter: We did not find any issues relating to colormaps.

    Results from rtransparent:
    • Thank you for including a conflict of interest statement. Authors are encouraged to include this statement when submitting to a journal.
    • Thank you for including a funding statement. Authors are encouraged to include this statement when submitting to a journal.
    • No protocol registration statement was detected.

    Results from scite Reference Check: We found no unreliable references.

    About SciScore

    SciScore is an automated tool that is designed to assist expert reviewers by finding and presenting formulaic information scattered throughout a paper in a standard, easy to digest format. SciScore checks for the presence and correctness of RRIDs (research resource identifiers), and for rigor criteria such as sex and investigator blinding. For details on the theoretical underpinning of rigor criteria and the tools shown here, including references cited, please follow this link.

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