Covid-19 Vaccine Effectiveness against the Omicron (B.1.1.529) Variant
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Abstract
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SciScore for 10.1101/2021.12.14.21267615: (What is this?)
Please note, not all rigor criteria are appropriate for all manuscripts.
Table 1: Rigor
Ethics not detected. Sex as a biological variable not detected. Randomization not detected. Blinding not detected. Power Analysis not detected. Table 2: Resources
No key resources detected.
Results from OddPub: We did not detect open data. We also did not detect open code. Researchers are encouraged to share open data when possible (see Nature blog).
Results from LimitationRecognizer: We detected the following sentences addressing limitations in the study:Nevertheless, there are some limitations and findings should be interpreted with caution. During this early period of circulation of the new variant, a large proportion of cases occurred among travellers. Individuals who reported travel in the preceding two …
SciScore for 10.1101/2021.12.14.21267615: (What is this?)
Please note, not all rigor criteria are appropriate for all manuscripts.
Table 1: Rigor
Ethics not detected. Sex as a biological variable not detected. Randomization not detected. Blinding not detected. Power Analysis not detected. Table 2: Resources
No key resources detected.
Results from OddPub: We did not detect open data. We also did not detect open code. Researchers are encouraged to share open data when possible (see Nature blog).
Results from LimitationRecognizer: We detected the following sentences addressing limitations in the study:Nevertheless, there are some limitations and findings should be interpreted with caution. During this early period of circulation of the new variant, a large proportion of cases occurred among travellers. Individuals who reported travel in the preceding two weeks were excluded from this analysis, however, this may not exclude all travellers and will not exclude contacts of travellers. This group is likely to have different exposure to the wider population and may also have different levels of vaccine coverage, therefore residual confounding may be present. Due to the relatively small number of cases of Omicron in the UK, there is significant uncertainty to our estimates and we are unable to break down estimates by population characteristics by that may affect vaccine effectiveness (such as age and clinical risk group).(18) In this analysis, our comparator group is unvaccinated individuals, who comprise a very small proportion of individuals in several age cohorts. These people are likely to differ from the general population according to characteristics that could confound our vaccine effectiveness estimates. In this analysis that covers all ages, this may be less of an issue than in analyses restricted to elderly populations. Furthermore, recent analyses using different control groups have found good concordance when using an unvaccinated control compared to relative vaccine effectiveness between those who have received a booster dose and those who have received two doses. B...
Results from TrialIdentifier: No clinical trial numbers were referenced.
Results from Barzooka: We did not find any issues relating to the usage of bar graphs.
Results from JetFighter: We did not find any issues relating to colormaps.
Results from rtransparent:- Thank you for including a conflict of interest statement. Authors are encouraged to include this statement when submitting to a journal.
- Thank you for including a funding statement. Authors are encouraged to include this statement when submitting to a journal.
- No protocol registration statement was detected.
Results from scite Reference Check: We found no unreliable references.
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