Mutations on RBD of SARS-CoV-2 Omicron variant result in stronger binding to human ACE2 receptor
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SciScore for 10.1101/2021.12.10.472102: (What is this?)
Please note, not all rigor criteria are appropriate for all manuscripts.
Table 1: Rigor
NIH rigor criteria are not applicable to paper type.Table 2: Resources
Software and Algorithms Sentences Resources The wild type and Omicron variant ACE2-RBD systems were both simulated for 2 × 500 ns using the GROMACS 5.1.2 package [24]. GROMACSsuggested: (GROMACS, RRID:SCR_014565)Pymol was used for molecular binding interface, water distributions, visualization, and rending model images [27]. Pymolsuggested: (PyMOL, RRID:SCR_000305)Results from OddPub: We did not detect open data. We also did not detect open code. Researchers are encouraged to share open data when possible (see Nature blog).
Results from LimitationRecognizer: An explicit section about the limitations of the techniques employed in this …SciScore for 10.1101/2021.12.10.472102: (What is this?)
Please note, not all rigor criteria are appropriate for all manuscripts.
Table 1: Rigor
NIH rigor criteria are not applicable to paper type.Table 2: Resources
Software and Algorithms Sentences Resources The wild type and Omicron variant ACE2-RBD systems were both simulated for 2 × 500 ns using the GROMACS 5.1.2 package [24]. GROMACSsuggested: (GROMACS, RRID:SCR_014565)Pymol was used for molecular binding interface, water distributions, visualization, and rending model images [27]. Pymolsuggested: (PyMOL, RRID:SCR_000305)Results from OddPub: We did not detect open data. We also did not detect open code. Researchers are encouraged to share open data when possible (see Nature blog).
Results from LimitationRecognizer: An explicit section about the limitations of the techniques employed in this study was not found. We encourage authors to address study limitations.Results from TrialIdentifier: No clinical trial numbers were referenced.
Results from Barzooka: We did not find any issues relating to the usage of bar graphs.
Results from JetFighter: We did not find any issues relating to colormaps.
Results from rtransparent:- Thank you for including a conflict of interest statement. Authors are encouraged to include this statement when submitting to a journal.
- Thank you for including a funding statement. Authors are encouraged to include this statement when submitting to a journal.
- No protocol registration statement was detected.
Results from scite Reference Check: We found no unreliable references.
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