1. SciScore for 10.1101/2021.11.29.21267006: (What is this?)

    Please note, not all rigor criteria are appropriate for all manuscripts.

    Table 1: Rigor

    EthicsIRB: This study was registered, number ISRCTN11041050, and received approval from the Berkshire Research Ethics Committee on 22 May 2020.
    Sex as a biological variablenot detected.
    Randomizationnot detected.
    Blindingnot detected.
    Power Analysisnot detected.

    Table 2: Resources

    Software and Algorithms
    5 We used STATA software (version 15.1; StataCorp LLC, College Station, TX, USA) for all analyses.
    suggested: (Stata, RRID:SCR_012763)
    suggested: (Stata, RRID:SCR_012763)

    Results from OddPub: Thank you for sharing your code and data.

    Results from LimitationRecognizer: We detected the following sentences addressing limitations in the study:
    The most important limitation of our study is the relatively small number of participants continuing to contribute follow-up time to key vaccination exposures: unvaccinated, ChAdOx1 and BNT162b2 short interval. This particularly affects the precision of estimates and our ability to assess potential waning following two-doses of ChAdOx1, and >15 months after primary infection in unvaccinated participants. We consider that the strengths of our study design and speed of vaccine deployment significantly limit the impact of depletion-of-susceptible bias (which particularly affects studies on vaccine-waning),19 however we recognise some residual confounding may remain.

    Results from TrialIdentifier: We found the following clinical trial numbers in your paper:


    Results from Barzooka: We did not find any issues relating to the usage of bar graphs.

    Results from JetFighter: We did not find any issues relating to colormaps.

    Results from rtransparent:
    • Thank you for including a conflict of interest statement. Authors are encouraged to include this statement when submitting to a journal.
    • Thank you for including a funding statement. Authors are encouraged to include this statement when submitting to a journal.
    • No protocol registration statement was detected.

    Results from scite Reference Check: We found no unreliable references.

    About SciScore

    SciScore is an automated tool that is designed to assist expert reviewers by finding and presenting formulaic information scattered throughout a paper in a standard, easy to digest format. SciScore checks for the presence and correctness of RRIDs (research resource identifiers), and for rigor criteria such as sex and investigator blinding. For details on the theoretical underpinning of rigor criteria and the tools shown here, including references cited, please follow this link.

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