Resolving SARS-CoV-2 CD4+ T cell specificity via reverse epitope discovery
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SciScore for 10.1101/2021.11.19.469229: (What is this?)
Please note, not all rigor criteria are appropriate for all manuscripts.
Table 1: Rigor
NIH rigor criteria are not applicable to paper type.Table 2: Resources
Software and Algorithms Sentences Resources Identification of motifs in TCR amino acid sequences using TCRdist: We used the TCRdist implementation in conga python package to calculate pairwise TCRdist between unique abTCR sequences and plot sequence logos for TCR motifs (Schattgen et al., 2021). pythonsuggested: (IPython, RRID:SCR_001658)Results from OddPub: Thank you for sharing your code and data.
Results from LimitationRecognizer: An explicit section about the limitations of the techniques employed in this study was not found. We encourage authors to address study limitations.Results from TrialIdentifier: We found the following …
SciScore for 10.1101/2021.11.19.469229: (What is this?)
Please note, not all rigor criteria are appropriate for all manuscripts.
Table 1: Rigor
NIH rigor criteria are not applicable to paper type.Table 2: Resources
Software and Algorithms Sentences Resources Identification of motifs in TCR amino acid sequences using TCRdist: We used the TCRdist implementation in conga python package to calculate pairwise TCRdist between unique abTCR sequences and plot sequence logos for TCR motifs (Schattgen et al., 2021). pythonsuggested: (IPython, RRID:SCR_001658)Results from OddPub: Thank you for sharing your code and data.
Results from LimitationRecognizer: An explicit section about the limitations of the techniques employed in this study was not found. We encourage authors to address study limitations.Results from TrialIdentifier: We found the following clinical trial numbers in your paper:
Identifier Status Title NCT04762186 Not yet recruiting Adoptive SARS-CoV-2 Specific T Cell Transfer in Patients at … Results from Barzooka: We did not find any issues relating to the usage of bar graphs.
Results from JetFighter: We did not find any issues relating to colormaps.
Results from rtransparent:- Thank you for including a conflict of interest statement. Authors are encouraged to include this statement when submitting to a journal.
- Thank you for including a funding statement. Authors are encouraged to include this statement when submitting to a journal.
- No protocol registration statement was detected.
Results from scite Reference Check: We found no unreliable references.
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