COVID-19 Pandemic Impact on Sexually Transmitted Infection Testing in a College Setting

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1. 

   ScreenIT

   Oct 12, 2021

   SciScore for 10.1101/2021.10.08.21264716: (What is this?)

   Please note, not all rigor criteria are appropriate for all manuscripts.

   Table 1: Rigor

   Ethics	IRB: An Institutional Review Board (IRB) approved the protocol.
   Sex as a biological variable	We reported total data for number of STI tests done, positive rate for STI and percentage of compliance and we then assessed female and male reports separately for all three outcomes.
   Randomization	not detected.
   Blinding	not detected.
   Power Analysis	not detected.

   Table 2: Resources

   Software and Algorithms
   Sentences	Resources
   To measure number of tests done, positive rate, and compliance to follow up testing for STIs during the COVID-19 pandemic, we used: Definitions:	Definitions suggested: None

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   Results from OddPub: We did not detect open data. We also did not detect open code. Researchers are encouraged to share …

   SciScore for 10.1101/2021.10.08.21264716: (What is this?)

   Please note, not all rigor criteria are appropriate for all manuscripts.

   Table 1: Rigor

   Ethics	IRB: An Institutional Review Board (IRB) approved the protocol.
   Sex as a biological variable	We reported total data for number of STI tests done, positive rate for STI and percentage of compliance and we then assessed female and male reports separately for all three outcomes.
   Randomization	not detected.
   Blinding	not detected.
   Power Analysis	not detected.

   Table 2: Resources

   Software and Algorithms
   Sentences	Resources
   To measure number of tests done, positive rate, and compliance to follow up testing for STIs during the COVID-19 pandemic, we used: Definitions:	Definitions suggested: None

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   Results from OddPub: We did not detect open data. We also did not detect open code. Researchers are encouraged to share open data when possible (see Nature blog).

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   Results from LimitationRecognizer: We detected the following sentences addressing limitations in the study:

   Overall, given the changes in access to routine clinical health services based on clinic limitations as well as studies demonstrating hesitancy on behalf of patients related to COVID-19, the finding of reduced testing is expected. Positive STI rates increased for both males and females.22 When analyzed by sex, historical data shows the percentage of positivity was higher in male students, consistent with males more often testing because of symptoms.24 Additionally, the finding of higher positivity with lower number of tests overall is likely due to triaging of patients and recommendation and facilitation of testing for those at highest risk of infection, including those with symptoms, known contact, or sexual behaviors associated with higher risk for infections. While appearing that we had a more efficient means of testing given the increased positivity rate in setting of reduced testing overall, it is likely that by adhering to the triaging, which was in line with CDC guidance at the time, many asymptomatic infections were missed. Many of these screens often occur during the context of wellness visits, which were primarily completed through telehealth at UHS during this time period. These asymptomatic infections are especially common in women, as well as typical of extragenital site infections, which make up the majority of chlamydia and gonorrhea infections in MSM.7 These infections can be associated with serious outcomes, such as PID and infertility in women and an increas...

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   Results from TrialIdentifier: No clinical trial numbers were referenced.

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   Results from Barzooka: We did not find any issues relating to the usage of bar graphs.

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   Results from JetFighter: We did not find any issues relating to colormaps.

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   Results from rtransparent:

   • Thank you for including a conflict of interest statement. Authors are encouraged to include this statement when submitting to a journal.
   • Thank you for including a funding statement. Authors are encouraged to include this statement when submitting to a journal.
   • No protocol registration statement was detected.

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   Results from scite Reference Check: We found no unreliable references.

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   Read the original source
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   Version published to 10.1101/2021.10.08.21264716v1 on medRxiv

   Oct 9, 2021