Cardiovascular Mortality During the COVID-19 Pandemics in a Large Brazilian City: A Comprehensive Analysis

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Abstract

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  1. SciScore for 10.1101/2021.10.08.21264699: (What is this?)

    Please note, not all rigor criteria are appropriate for all manuscripts.

    Table 1: Rigor

    Ethicsnot detected.
    Sex as a biological variablenot detected.
    Randomizationnot detected.
    Blindingnot detected.
    Power Analysisnot detected.

    Table 2: Resources

    No key resources detected.


    Results from OddPub: We did not detect open data. We also did not detect open code. Researchers are encouraged to share open data when possible (see Nature blog).


    Results from LimitationRecognizer: We detected the following sentences addressing limitations in the study:
    Our study has limitations. Because COVID-19 tests were not widely available in the community setting, out-of-hospital deaths may have been misdiagnosed, either over or underestimated deaths by CVD. Moreover, quality of death certificates may have worsen during the pandemic.51 However, no changes in the pattern of deaths under ICD-10 Chapter XVIII, which includes ill-defined causes of deaths, was found in our analysis, suggesting that this was not a major issue. Importantly, because our aim was to understand the indirect impact of the pandemic on CVD, we did not include in the present analysis the cardiovascular deaths related to COVID-19. As such, if COVID-19 was considered the underlying cause of death according to the World Health Organization protocols, and there was an associated cardiovascular outcome in the death certificate, this outcome was not included in the present analysis,22,52 as it would require an analysis of multiple causes of death.52 Another limitation refers to the fact that only public hospitalizations were analysed, due to availability of data. However, there was no substantial changes in the number of individuals with private health insurance in the city during the period.16 While the definition of out-of-hospital cause of death was described as a potential limitation, the same does not occur for in-hospital mortality, as hospitalizations for COVID-19 had to be confirmed by laboratory tests (RT-PCR or serology) that, although not widely available at the...

    Results from TrialIdentifier: No clinical trial numbers were referenced.


    Results from Barzooka: We did not find any issues relating to the usage of bar graphs.


    Results from JetFighter: We did not find any issues relating to colormaps.


    Results from rtransparent:
    • Thank you for including a conflict of interest statement. Authors are encouraged to include this statement when submitting to a journal.
    • Thank you for including a funding statement. Authors are encouraged to include this statement when submitting to a journal.
    • No protocol registration statement was detected.

    Results from scite Reference Check: We found no unreliable references.


    About SciScore

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