Protection against Covid-19 by BNT162b2 Booster across Age Groups

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Abstract

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  1. Jorge Salinas

    Review 2: "Protection Across Age Groups of BNT162b2 Vaccine Booster against Covid-19"

    This paper claims that compared to people who only received two doses of the Pfizer vaccine, those who additionally received the booster dose are less likely to have SARS CoV 2 infection, severe illness, and death. Both reviewers agree on the robustness of the study methods.

  2. Arthur Reingold

    Review 1: "Protection Across Age Groups of BNT162b2 Vaccine Booster against Covid-19"

    This paper claims that compared to people who only received two doses of the Pfizer vaccine, those who additionally received the booster dose are less likely to have SARS CoV 2 infection, severe illness, and death. Both reviewers agree on the robustness of the study methods.

  3. SciScore for 10.1101/2021.10.07.21264626: (What is this?)

    Please note, not all rigor criteria are appropriate for all manuscripts.

    Table 1: Rigor

    EthicsIRB: For individuals who were abroad in part of the study period, we excluded days at risk and COVID-19 infections during their stay abroad and the 10 days following their return to Israel. OVERSIGHT: The study was approved by the institutional review board of the Sheba Medical Center (Helsinki approval number: SMC-8228-21).
    Sex as a biological variablenot detected.
    Randomizationnot detected.
    Blindingnot detected.
    Power Analysisnot detected.

    Table 2: Resources

    No key resources detected.


    Results from OddPub: We did not detect open data. We also did not detect open code. Researchers are encouraged to share open data when possible (see Nature blog).


    Results from LimitationRecognizer: An explicit …