SARS-CoV-2 neutralising antibodies in Dogs and Cats in the United Kingdom

Article activity feed

1. 

   ScreenIT

   Jul 1, 2021

   SciScore for 10.1101/2021.06.23.449594: (What is this?)

   Please note, not all rigor criteria are appropriate for all manuscripts.

   Table 1: Rigor

   Ethics	IRB: Ethical approval to collect electronic health data (SAVSNET) and physical samples from participating laboratories (National Virtual Biobank) was granted by the Research Ethics Committee at the University of Liverpool (RETH000964).
   Sex as a biological variable	not detected.
   Randomization	not detected.
   Blinding	not detected.
   Power Analysis	not detected.
   Cell Line Authentication	not detected.

   Table 2: Resources

   Experimental Models: Cell Lines
   Sentences	Resources
   The virus/serum mixture was then inoculated onto Vero E6 cells, incubated at 37°C for 1 h, and overlaid as in standard plaque assays [27].	Vero E6 suggested: None

   ---

   Results from OddPub: We did not detect open data. We also did not detect open code. …

   SciScore for 10.1101/2021.06.23.449594: (What is this?)

   Please note, not all rigor criteria are appropriate for all manuscripts.

   Table 1: Rigor

   Ethics	IRB: Ethical approval to collect electronic health data (SAVSNET) and physical samples from participating laboratories (National Virtual Biobank) was granted by the Research Ethics Committee at the University of Liverpool (RETH000964).
   Sex as a biological variable	not detected.
   Randomization	not detected.
   Blinding	not detected.
   Power Analysis	not detected.
   Cell Line Authentication	not detected.

   Table 2: Resources

   Experimental Models: Cell Lines
   Sentences	Resources
   The virus/serum mixture was then inoculated onto Vero E6 cells, incubated at 37°C for 1 h, and overlaid as in standard plaque assays [27].	Vero E6 suggested: None

   ---

   Results from OddPub: We did not detect open data. We also did not detect open code. Researchers are encouraged to share open data when possible (see Nature blog).

   ---

   Results from LimitationRecognizer: We detected the following sentences addressing limitations in the study:

   The major limitations of such a system are the relatively sparse data available for each sample such that individual animals, that are not identifiable, may have been sampled twice or have come from the same household. In addition, such samples lack detailed information on the health of the animals and whether they were from a COVID-19-positive household. However, acquiring such samples from the UK Virtual Biobank, offers a responsive resource for studying national patterns of disease in UK pets [25]. We report here the detection of SARS-CoV-2 neutralising antibodies during the second wave of human infections in the UK. Other groups have previously reported that cats and dogs can become infected, likely through their interactions with humans. Although animal-to-animal transmission has been reported, for example on mink farms and in experimental infections [18–20, 22, 34], the small numbers of companion animals testing positive in the field suggest that pets are not currently acting as a significant reservoir for infection, and that the pandemic will be controlled by measures largely focussed on minimising human-to-human transmission. However, studies like that presented here strongly argue for continued surveillance of in-contact, susceptible animal species, which will help determine whether in the future, more targeted control measures are needed for pet animals, particularly in regions that are gaining control of infection in their human populations.

   ---

   Results from TrialIdentifier: No clinical trial numbers were referenced.

   ---

   Results from Barzooka: We did not find any issues relating to the usage of bar graphs.

   ---

   Results from JetFighter: We did not find any issues relating to colormaps.

   ---

   Results from rtransparent:

   • Thank you for including a conflict of interest statement. Authors are encouraged to include this statement when submitting to a journal.
   • Thank you for including a funding statement. Authors are encouraged to include this statement when submitting to a journal.
   • No protocol registration statement was detected.

   ---

   Results from scite Reference Check: We found no unreliable references.

   ---

   Read the original source
2. 

   Version published to 10.1101/2021.06.23.449594v1 on bioRxiv

   Jun 23, 2021
3. Version published to 10.1016/j.crviro.2021.100011

   Jan 1, 2021