SARS-CoV-2 susceptibility and COVID-19 disease severity are associated with genetic variants affecting gene expression in a variety of tissues
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SciScore for 10.1101/2021.05.10.21256423: (What is this?)
Please note, not all rigor criteria are appropriate for all manuscripts.
Table 1: Rigor
Ethics not detected. Sex as a biological variable not detected. Randomization not detected. Blinding not detected. Power Analysis not detected. Table 2: Resources
Software and Algorithms Sentences Resources We used bedtools merge 56 to identify 24 genome-wide-significant unique loci. bedtoolssuggested: (BEDTools, RRID:SCR_006646)We obtained a token from https://ldlink.nci.nih.gov/?tab=apiaccess and interrogated the 1000 Genomes LD structure using the LDproxy function. https://ldlink.nci.nih.gov/suggested: (LDMatrix, RRID:SCR_017391)1000 Genomessuggested: (1000 Genomes Project and AWS, RRID:SCR_008801)Results from OddPub: We did not detect open data. We also did not detect open code. Researchers are encouraged …
SciScore for 10.1101/2021.05.10.21256423: (What is this?)
Please note, not all rigor criteria are appropriate for all manuscripts.
Table 1: Rigor
Ethics not detected. Sex as a biological variable not detected. Randomization not detected. Blinding not detected. Power Analysis not detected. Table 2: Resources
Software and Algorithms Sentences Resources We used bedtools merge 56 to identify 24 genome-wide-significant unique loci. bedtoolssuggested: (BEDTools, RRID:SCR_006646)We obtained a token from https://ldlink.nci.nih.gov/?tab=apiaccess and interrogated the 1000 Genomes LD structure using the LDproxy function. https://ldlink.nci.nih.gov/suggested: (LDMatrix, RRID:SCR_017391)1000 Genomessuggested: (1000 Genomes Project and AWS, RRID:SCR_008801)Results from OddPub: We did not detect open data. We also did not detect open code. Researchers are encouraged to share open data when possible (see Nature blog).
Results from LimitationRecognizer: An explicit section about the limitations of the techniques employed in this study was not found. We encourage authors to address study limitations.Results from TrialIdentifier: No clinical trial numbers were referenced.
Results from Barzooka: We did not find any issues relating to the usage of bar graphs.
Results from JetFighter: We did not find any issues relating to colormaps.
Results from rtransparent:- Thank you for including a conflict of interest statement. Authors are encouraged to include this statement when submitting to a journal.
- Thank you for including a funding statement. Authors are encouraged to include this statement when submitting to a journal.
- No protocol registration statement was detected.
Results from scite Reference Check: We found no unreliable references.
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