Structures of the TRPM5 channel elucidate mechanisms of activation and inhibition

Zheng Ruan
Emery Haley
Ian J. Orozco
Mark Sabat
Richard Myers
Rebecca Roth
Juan Du
Wei Lü

Read the full article

Discuss this preprint

Start a discussion What are Sciety discussions?

Listed in

@kenton_swartz's saved articles (kenton_swartz)

Log in to save this article

Abstract

No abstract available

Version published to 10.1038/s41594-021-00607-4
Jun 24, 2021
Version published to 10.1101/2021.03.25.437100 on bioRxiv
Mar 26, 2021

Temperature-dependent ligand relocation reveals plasticity of TRPM4 inhibition

This article has 5 authors:
1. Dominic Schneiter
2. Jean-Sébastien Rougier
3. Hugues Abriel
4. Henning Stahlberg
5. Babatunde Ekundayo
This article has no evaluationsLatest version May 14, 2026
Deep mutational scan of the pore of the cold-sensing TRPM8 channel

This article has 12 authors:
1. Averi Pike
2. Vincent Le
3. Ashlin Turner
4. Catalina Galván
5. Ashley Vazhavilla
6. Richard Salinas
7. Matt Bramble
8. Dennis C. Wylie
9. Jessica W. Podnar
10. Ian Hoskins
11. Can Cenik
12. Andrés Jara-Oseguera
This article has no evaluationsLatest version May 1, 2026
Activation by statins unveils two putative agonist binding sites in the pore domain of TRPA1

This article has 5 authors:
1. Justyna B. Startek
2. Alina Milici
3. Katharina Held
4. Ariel Talavera
5. Karel Talavera
This article has no evaluationsLatest version May 12, 2026