Initial observations on age, gender, BMI and hypertension in antibody responses to SARS-CoV-2 BNT162b2 vaccine
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SciScore for 10.1101/2021.02.24.21251664: (What is this?)
Please note, not all rigor criteria are appropriate for all manuscripts.
Table 1: Rigor
Institutional Review Board Statement IACUC: The study protocol complied with the tenets of the Helsinki declaration and was approved by the institutional scientific ethics committee (protocol RS1463/21).
Consent: All the enrolled participants met the following inclusion criteria: 1) provided written informed consent 2) age between 18-75 years, 3) health workers employed at the Istituti Fisioterapici Ospitalieri (IFO), 4) vaccinated at the Istituti Fisioterapici Ospitalieri (IFO).Randomization not detected. Blinding not detected. Power Analysis not detected. Sex as a biological variable Findings: 248 HWCs were analysed, 158 women (63.7%) and 90 men (36.3%). Table 2: Resources
Antibodies Sentences Resources Quan… SciScore for 10.1101/2021.02.24.21251664: (What is this?)
Please note, not all rigor criteria are appropriate for all manuscripts.
Table 1: Rigor
Institutional Review Board Statement IACUC: The study protocol complied with the tenets of the Helsinki declaration and was approved by the institutional scientific ethics committee (protocol RS1463/21).
Consent: All the enrolled participants met the following inclusion criteria: 1) provided written informed consent 2) age between 18-75 years, 3) health workers employed at the Istituti Fisioterapici Ospitalieri (IFO), 4) vaccinated at the Istituti Fisioterapici Ospitalieri (IFO).Randomization not detected. Blinding not detected. Power Analysis not detected. Sex as a biological variable Findings: 248 HWCs were analysed, 158 women (63.7%) and 90 men (36.3%). Table 2: Resources
Antibodies Sentences Resources Quantitative measurement of IgG antibodies against S1/S2 antigens of SARS-CoV-2 was performed with a commercial chemiluminescent immunoassay (The LIAISON® SARS-CoV-2 S1/S2 IgG, test Diasorin, Italy) according to the manufacturer’s instruction. S1/S2suggested: NoneFigure 2: Levels of anti SARS-CoV-2 spike IgG antibody by BMI classes. anti SARS-CoV-2 spike IgGsuggested: NoneSoftware and Algorithms Sentences Resources Statistical analysis was done using SPSS Statistics software version 21 SPSSsuggested: (SPSS, RRID:SCR_002865)Results from OddPub: We did not detect open data. We also did not detect open code. Researchers are encouraged to share open data when possible (see Nature blog).
Results from LimitationRecognizer: An explicit section about the limitations of the techniques employed in this study was not found. We encourage authors to address study limitations.Results from TrialIdentifier: We found the following clinical trial numbers in your paper:
Identifier Status Title ISRCTN55371988 NA NA Results from Barzooka: We did not find any issues relating to the usage of bar graphs.
Results from JetFighter: We did not find any issues relating to colormaps.
Results from rtransparent:- Thank you for including a conflict of interest statement. Authors are encouraged to include this statement when submitting to a journal.
- Thank you for including a funding statement. Authors are encouraged to include this statement when submitting to a journal.
- Thank you for including a protocol registration statement.
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