Community Transmission of SARS-CoV-2 by Surfaces: Risks and Risk Reduction Strategies
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Abstract
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SciScore for 10.1101/2020.11.20.20220749: (What is this?)
Please note, not all rigor criteria are appropriate for all manuscripts.
Table 1: Rigor
NIH rigor criteria are not applicable to paper type.Table 2: Resources
No key resources detected.
Results from OddPub: Thank you for sharing your code and data.
Results from LimitationRecognizer: We detected the following sentences addressing limitations in the study:The exponential dose-response model in particular suffers from a number of limitations: the model is based on data of SARS-CoV and Murine hepatitis virus (MHV-1) infection in mice by intranasal administration40,41. Extrapolating the model from mice to people and from MHV-1 and SARS-CoV to SARS-CoV-2, introduces uncertainty in infection risk estimates, but – in accordance with current best practice 59 – we did not consider this here. …
SciScore for 10.1101/2020.11.20.20220749: (What is this?)
Please note, not all rigor criteria are appropriate for all manuscripts.
Table 1: Rigor
NIH rigor criteria are not applicable to paper type.Table 2: Resources
No key resources detected.
Results from OddPub: Thank you for sharing your code and data.
Results from LimitationRecognizer: We detected the following sentences addressing limitations in the study:The exponential dose-response model in particular suffers from a number of limitations: the model is based on data of SARS-CoV and Murine hepatitis virus (MHV-1) infection in mice by intranasal administration40,41. Extrapolating the model from mice to people and from MHV-1 and SARS-CoV to SARS-CoV-2, introduces uncertainty in infection risk estimates, but – in accordance with current best practice 59 – we did not consider this here. Nevertheless, dose-response relationships derived from animal studies tend to be more conservative60. An additional limitation is that the dose-response relationship was determined using virus as measured in units of Plaque Forming Units (PFU) and therefore a ratio of genome copies to PFU is needed. The assumed range of ratios of 1:100 to 1:1000 for genome copies to viable virus is based on Influenza, along with the sparse data currently available for SARS-CoV-2. Data quantifying viable virus on fomites in communities would be the “gold standard”, but detection of viable virus is unlikely given previously observed concentrations of SARS-CoV-2 RNA align with estimates of viable virus of <1 / 100 cm2. Because of the uncertainties in parameter estimates, QMRA estimates of relative risk reduction from interventions are viewed as more reliable because potential biases in data are incorporated into both the intervention and control risk estimates58. Additional model characteristics likely influence risk estimates. Model parameters used for virus transfe...
Results from TrialIdentifier: No clinical trial numbers were referenced.
Results from Barzooka: We did not find any issues relating to the usage of bar graphs.
Results from JetFighter: We did not find any issues relating to colormaps.
Results from rtransparent:- Thank you for including a conflict of interest statement. Authors are encouraged to include this statement when submitting to a journal.
- Thank you for including a funding statement. Authors are encouraged to include this statement when submitting to a journal.
- No protocol registration statement was detected.
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