A systematic review of mask disinfection and reuse for SARS-CoV-2 (through July 10, 2020)
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Abstract
We conducted a systematic review of hygiene intervention effectiveness against SARS-CoV-2, including developing inclusion criteria, conducting the search, selecting articles for inclusion, and summarizing included articles. We reviewed 104,735 articles, and 109 articles meeting inclusion criteria were identified, with 33 additional articles identified from reference chaining. Herein, we describe results from 58 mask disinfection and reuse studies, where the majority of data were collected using N95 masks. Please note, no disinfection method consistently removed >3 log of virus irrespective of concentration, contact time, temperature, and humidity. However, results show it is possible to achieve >3 log reduction of SARS-CoV-2 using appropriate concentrations and contact times of chemical (ethanol, hydrogen peroxide, peracetic acid), radiation (PX-UV, UVGI), and thermal (autoclaving, heat) disinfection on N95 masks. N95 mask reuse and failure data indicate that hydrogen peroxide, heat, and UV-GI are promising for mask reuse, peracetic acid and PX-UV need more data, and autoclaving and ethanol lead to mask durability failures. Data on other mask types is limited. We thus recommend focusing guidelines and further research on the use of heat, hydrogen peroxide, and UVGI for N95 mask disinfection/reuse. All of these disinfection options could be investigated for use in LMIC and humanitarian contexts.
TOC Art
Synopsis
In resource-limited contexts, N95s are reused. We recommend using heat, hydrogen peroxide, or UVGI to disinfect and reuse N95 masks.
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SciScore for 10.1101/2020.11.11.20229880: (What is this?)
Please note, not all rigor criteria are appropriate for all manuscripts.
Table 1: Rigor
Institutional Review Board Statement not detected. Randomization not detected. Blinding not detected. Power Analysis not detected. Sex as a biological variable not detected. Table 2: Resources
Software and Algorithms Sentences Resources References were stored in Microsoft Excel (Redmond, WA, USA) and Endnote (Philadelphia, PA, USA), and duplicates were deleted. Microsoft Excelsuggested: (Microsoft Excel, RRID:SCR_016137)Inclusion Criteria: Inclusion criteria were defined according to the populations, interventions, comparisons, outcomes, and study type (PICOS) framework, a model recommended by the Cochrane Library to structure rigorous reviews on health-related questions 10. Cochrane Librarysuggested: (Cochrane …SciScore for 10.1101/2020.11.11.20229880: (What is this?)
Please note, not all rigor criteria are appropriate for all manuscripts.
Table 1: Rigor
Institutional Review Board Statement not detected. Randomization not detected. Blinding not detected. Power Analysis not detected. Sex as a biological variable not detected. Table 2: Resources
Software and Algorithms Sentences Resources References were stored in Microsoft Excel (Redmond, WA, USA) and Endnote (Philadelphia, PA, USA), and duplicates were deleted. Microsoft Excelsuggested: (Microsoft Excel, RRID:SCR_016137)Inclusion Criteria: Inclusion criteria were defined according to the populations, interventions, comparisons, outcomes, and study type (PICOS) framework, a model recommended by the Cochrane Library to structure rigorous reviews on health-related questions 10. Cochrane Librarysuggested: (Cochrane Library, RRID:SCR_013000)Analysis: Data were managed and analyzed in Excel and Sheets. Excelsuggested: NoneResults from OddPub: Thank you for sharing your data.
Results from LimitationRecognizer: An explicit section about the limitations of the techniques employed in this study was not found. We encourage authors to address study limitations.Results from TrialIdentifier: No clinical trial numbers were referenced.
Results from Barzooka: We did not find any issues relating to the usage of bar graphs.
Results from JetFighter: We did not find any issues relating to colormaps.
Results from rtransparent:- Thank you for including a conflict of interest statement. Authors are encouraged to include this statement when submitting to a journal.
- Thank you for including a funding statement. Authors are encouraged to include this statement when submitting to a journal.
- No protocol registration statement was detected.
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