COVID-19 in patients with hepatobiliary and pancreatic diseases in East London: a single-centre cohort study
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SciScore for 10.1101/2020.09.07.20189621: (What is this?)
Please note, not all rigor criteria are appropriate for all manuscripts.
Table 1: Rigor
Institutional Review Board Statement IRB: The EL-PaC-Epidem study was approved by the East of England - Essex Research Ethics Committee (19/EE/0163; May 17, 2019) and supported by the NHS Confidentiality Advisory Group for collecting and processing confidential patient information without consent (19/CAG/0219; January 17, 2020).
Consent: The EL-PaC-Epidem study was approved by the East of England - Essex Research Ethics Committee (19/EE/0163; May 17, 2019) and supported by the NHS Confidentiality Advisory Group for collecting and processing confidential patient information without consent (19/CAG/0219; January 17, 2020).Randomization not detected. Blinding not detected. Power Analysis not detected. Sex … SciScore for 10.1101/2020.09.07.20189621: (What is this?)
Please note, not all rigor criteria are appropriate for all manuscripts.
Table 1: Rigor
Institutional Review Board Statement IRB: The EL-PaC-Epidem study was approved by the East of England - Essex Research Ethics Committee (19/EE/0163; May 17, 2019) and supported by the NHS Confidentiality Advisory Group for collecting and processing confidential patient information without consent (19/CAG/0219; January 17, 2020).
Consent: The EL-PaC-Epidem study was approved by the East of England - Essex Research Ethics Committee (19/EE/0163; May 17, 2019) and supported by the NHS Confidentiality Advisory Group for collecting and processing confidential patient information without consent (19/CAG/0219; January 17, 2020).Randomization not detected. Blinding not detected. Power Analysis not detected. Sex as a biological variable not detected. Table 2: Resources
No key resources detected.
Results from OddPub: We did not detect open data. We also did not detect open code. Researchers are encouraged to share open data when possible (see Nature blog).
Results from LimitationRecognizer: We detected the following sentences addressing limitations in the study:Our study also has some important limitations. In our cohort definition, only patients visiting BHNT hospitals and who were given a confirmed COVID-19 diagnosis code or tested positive for SARS-CoV-2 RNA were considered as having COVID-19. This may have resulted in some patients being incorrectly identified as not having COVID-19, particularly if they had a positive swab test via NHS coronavirus test sites or using a home test kit. However, our cohort had specific medical conditions with a high prevalence of comorbidities listed under the NHS categorisation of higher risk populations.3 Any manifestation of COVID-19 related symptoms would have likely resulted in these patients receiving treatment at one of the BHNT hospitals, and hence we were fairly confident on identifying all clinically relevant SARS-CoV-2 infections in our cohort within the three East London boroughs. A related limitation is associated with the confirmation of East London residency for the study cohort. Patients’ addresses (current or historic) are not collected under the umbrella study, which considers patients with HPB conditions (with the exception of cancer) treated or managed at BHNT hospitals as East London residents during the time of their care. The Royal London Hospital hosts one of the largest HPB centres in England, and supports suspected or confirmed HPB cancer patients from nearby geographical areas. As the umbrella study cohort is historic, we acknowledged the probability of people moving awa...
Results from TrialIdentifier: No clinical trial numbers were referenced.
Results from Barzooka: We did not find any issues relating to the usage of bar graphs.
Results from JetFighter: We did not find any issues relating to colormaps.
Results from rtransparent:- Thank you for including a conflict of interest statement. Authors are encouraged to include this statement when submitting to a journal.
- Thank you for including a funding statement. Authors are encouraged to include this statement when submitting to a journal.
- No protocol registration statement was detected.
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