Worsening of pre-existing psychiatric conditions during the COVID-19 pandemic
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Abstract
This study anonymously examined 2,734 psychiatric patients worldwide for worsening of their pre-existing psychiatric condition during the COVID-19 pandemic. Valid responses mainly from 12 featured countries indicated self-reported worsening of psychiatric conditions in 2/3 rd of the patients assessed that was validated through their significantly higher scores on scales for general psychological disturbance, post-traumatic stress disorder, and depression. Female gender, feeling no control of the situation and reporting dissatisfaction with the response of the state during the COVID-19 pandemic, and reduced interaction with family and friends increased the worsening of pre-existing psychiatric conditions, whereas optimism, ability to share concerns with family and friends and using social media like usual were associated with less worsening. An independent clinical investigation from the USA confirmed worsening of psychiatric conditions during the COVID-19 pandemic based on identification of new symptoms that necessiated clinical interventions such as dose adjustment or starting new medications in more than half of the patients.
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SciScore for 10.1101/2020.05.28.20116178: (What is this?)
Please note, not all rigor criteria are appropriate for all manuscripts.
Table 1: Rigor
Institutional Review Board Statement Consent: Ethical Considerations: Informed consent was obtained from each survey and clinical participant to allow anonymous recording, analysis, and publication of their answers.
IRB: The study procedures were reviewed and approved by University of Zurich Research Office for Scientific Integrity and Cantonal Ethics Commission for the canton of Zurich (Switzerland; Appendix 3), Nencki Institute of Experimental Biology, Warsaw (Poland; Appendix 4), and the Faculty of Medicine, University of Tuzla, Tuzla (Bosnia and Herzegovina; Appendix 5).Randomization not detected. Blinding Clinical data for each patient was examined by clinic assistants blinded to the study design. SciScore for 10.1101/2020.05.28.20116178: (What is this?)
Please note, not all rigor criteria are appropriate for all manuscripts.
Table 1: Rigor
Institutional Review Board Statement Consent: Ethical Considerations: Informed consent was obtained from each survey and clinical participant to allow anonymous recording, analysis, and publication of their answers.
IRB: The study procedures were reviewed and approved by University of Zurich Research Office for Scientific Integrity and Cantonal Ethics Commission for the canton of Zurich (Switzerland; Appendix 3), Nencki Institute of Experimental Biology, Warsaw (Poland; Appendix 4), and the Faculty of Medicine, University of Tuzla, Tuzla (Bosnia and Herzegovina; Appendix 5).Randomization not detected. Blinding Clinical data for each patient was examined by clinic assistants blinded to the study design. Power Analysis not detected. Sex as a biological variable not detected. Table 2: Resources
Software and Algorithms Sentences Resources All figures were produced using the packages ggplot2 (Wickham et al., 2016) and CGPfunctions (Powell, 2020). ggplot2suggested: (ggplot2, RRID:SCR_014601)Results from OddPub: Thank you for sharing your data.
Results from LimitationRecognizer: An explicit section about the limitations of the techniques employed in this study was not found. We encourage authors to address study limitations.Results from TrialIdentifier: No clinical trial numbers were referenced.
Results from Barzooka: We did not find any issues relating to the usage of bar graphs.
Results from JetFighter: We did not find any issues relating to colormaps.
Results from rtransparent:- Thank you for including a conflict of interest statement. Authors are encouraged to include this statement when submitting to a journal.
- Thank you for including a funding statement. Authors are encouraged to include this statement when submitting to a journal.
- No protocol registration statement was detected.
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