Analysis of psychological state and clinical psychological intervention model of patients with COVID-19

  1. Lu Yang
  2. Danjuan Wu
  3. Yanbin Hou
  4. Xunqiang Wang
  5. Ni Dai
  6. Guanjun Wang
  7. Qing Yang
  8. Wenhui Zhao
  9. Zhongze Lou
  10. Yunxin Ji
  11. Liemin Ruan

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Abstract

Background

Patients with the 2019 coronavirus disease (COVID-19) have different degrees of psychological pain, such as anxiety and depression, which may related to their prognosis. Psychological intervention can be conducted in different ways to improve psychological pain and improve the treatment effect.

Objective

The present study aimed to investigate and analyze the psychological status of patients with COVID-19 during the course of illness, and to evaluate the effect and influencing factors of psychological crisis intervention, so as to explore the effective mode of clinical psychological intervention in acute patients under isolation environment.

Methods

A total of 143 persons participated in the study, including 26 patients diagnosed with COVID-19 in the isolation ward (COVID-19 group), 87 patients with general pneumonia in the observation ward (General Pneumonia group) and 30 healthy volunteers (Normal group). All the patients in the ward received comprehensive psychological intervention, including telephone psychological counseling (active and passive), self-adjustment of written materials and one-to-one psychological crisis intervention. Hamilton depression scale (HAMD) and Hamilton anxiety scale (HAMA) were used to evaluate the mental health status of all patients on the day of admission and 1 week after treatment.

Results

The scores of HAMA and HAMD of all patients (including isolation ward and observation ward) were significantly higher than the healthy volunteers at the time of admission. The total score of HAMA and HAMD in CVOID-19 group were both higher than that General Pneumonia group. After 1 week’s hospitalization with comprehensive psychological intervention, the scores of HAMA and HAMD in CVOID-19 group were significantly decreased.

Conclusion

Patients those who diagnosed with COVID-19 in the isolation ward and/or general pneumonia in observation ward have different degrees of anxiety, depression and sleep problems. While receiving antiviral treatment, patients also need psychological intervention. Comprehensive psychological intervention model has been proved to be effective.

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    SciScore for 10.1101/2020.03.22.20040899: (What is this?)

    Please note, not all rigor criteria are appropriate for all manuscripts.

    Table 1: Rigor

    Institutional Review Board StatementIRB: This study was approved by the Ethical Committee of Ningbo First Hospital (approval number: 2020-R042) and registered with the registry website http://www.chictr.org (registration number: ChiCTR2000030697).
    Consent: All participants in this study signed informed consent was obtained.
    Randomizationnot detected.
    Blindingnot detected.
    Power Analysisnot detected.
    Sex as a biological variableParticipants and study design: Collection 2020 February 5 to February 29 in view of the patient wards, including a total of 143 cases of 26 patients diagnosed with COVID-19 (COVID-19 group), who are in line with the interim guide diagnostic standards and national defense construction committee of the novel coronavirus pneumonia clinical trial program (version 6), diagnostic criteria, and nasopharyngeal swab specimen by Nucleic Acid Detection tests positive, of which 9 were men (35 per cent), 17 were women (65 per cent), and the age up to 86 years of age, minimum age of 27 years old, average age 56, mostly elderly patients.

    Table 2: Resources

    No key resources detected.

    Results from OddPub: We did not detect open data. We also did not detect open code. Researchers are encouraged to share open data when possible (see Nature blog).

    Results from LimitationRecognizer: We detected the following sentences addressing limitations in the study:
    This study has some limitations, as a result of the new champions league pneumonia in patients with less sample size, research results have representative need to further expand the study sample size, and the patient’s isolation and protection of medical personnel to carry out psychological intervention also caused a certain limit, psychological treatment in addition to the speech communication face to face, and even more expressions and gestures, and medical personnel’s body language also have obvious effect on patients with stable mood, such as watching a nod, take back, thumb, V gestures, etc., can better close distance, make patients feel be respected and valued, psychological assessment and psychological intervention on the patients better, promote disease rehabilitation. In addition, the psychological intervention without using case-control study, it is difficult to eliminate the effects of disease rehabilitation of mental state at the same time the author also noted that the COVID-19 outbreak is long-term and far-reaching impact on patients, as the patients’ rehabilitation home may appear new problems such as post-traumatic stress disorder, at present the related content need further follow-up, relevant data also in the collecting and organizing of further, we will further complete the next stage.

    Results from TrialIdentifier: No clinical trial numbers were referenced.

    Results from Barzooka: We did not find any issues relating to the usage of bar graphs.

    Results from JetFighter: We did not find any issues relating to colormaps.

    Results from rtransparent:
    • Thank you for including a conflict of interest statement. Authors are encouraged to include this statement when submitting to a journal.
    • Thank you for including a funding statement. Authors are encouraged to include this statement when submitting to a journal.
    • No protocol registration statement was detected.

    About SciScore

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  2. Version published to 10.1101/2020.03.22.20040899v1 on medRxiv