Global Reduction in Morbidity and Mortality Due to Vaccine Development, 1950-2021.

Introduction Vaccines have significantly reduced global morbidity and mortality from deadly infectious diseases during the last 70 years. Aim This study furnishes a systematic vaccine development and deployment analysis from 1950 to 2021. Methodology The retrieved data from the World Health Organization (WHO), national health registries, and Global Burden of Disease (GBD) were used in this paper to assess data about numerous infectious diseases, and the trends in vaccine-preventable diseases (VPDs) were assessed. Results The assessed information on the following diseases was analyzed: polio, measles, pertussis, tetanus, diphtheria, HPV, hepatitis B, and COVID-19. A significant decline was observed in disease burden, with measles-associated deaths declining by 94% and polio cases falling by over 99%. In addition to a dramatic fall in other diseases or death-related diseases due to vaccine developments and new technologies used in modern vaccine production techniques. In Conclusions conclusion, this finding underscores the vital role of immunization programs in improving public health and epidemiological outcomes. This vaccine program achievement is more pronounced in low and middle-income countries.