Characterization of Prolonged COVID-19 Symptoms in an Outpatient Telemedicine Clinic
This article has been Reviewed by the following groups
Listed in
- Evaluated articles (ScreenIT)
Abstract
We identified patients with coronavirus disease 2019 in a telemedicine clinic who requested ongoing follow-up calls 6 weeks after symptom onset. In this group, respiratory symptoms are the most common complaints, asthma and lung disease are frequent comorbidities, and patients often have not returned to work or usual activity.
Article activity feed
-
-
SciScore for 10.1101/2020.07.05.20146886: (What is this?)
Please note, not all rigor criteria are appropriate for all manuscripts.
Table 1: Rigor
Institutional Review Board Statement not detected. Randomization not detected. Blinding not detected. Power Analysis not detected. Sex as a biological variable not detected. Table 2: Resources
Software and Algorithms Sentences Resources Symptom results were analyzed in Microsoft Excel using descriptive statistics. Microsoft Excelsuggested: (Microsoft Excel, RRID:SCR_016137)Comparison between prolonged symptom group and the rest of the VOMC were conducted with Fisher’s exact test using SPSS version 26 (IBM). SPSSsuggested: (SPSS, RRID:SCR_002865)Results from OddPub: We did not detect open data. We also did not detect open code. Researchers are encouraged to share open data when possible (see Nature blog).
Results …SciScore for 10.1101/2020.07.05.20146886: (What is this?)
Please note, not all rigor criteria are appropriate for all manuscripts.
Table 1: Rigor
Institutional Review Board Statement not detected. Randomization not detected. Blinding not detected. Power Analysis not detected. Sex as a biological variable not detected. Table 2: Resources
Software and Algorithms Sentences Resources Symptom results were analyzed in Microsoft Excel using descriptive statistics. Microsoft Excelsuggested: (Microsoft Excel, RRID:SCR_016137)Comparison between prolonged symptom group and the rest of the VOMC were conducted with Fisher’s exact test using SPSS version 26 (IBM). SPSSsuggested: (SPSS, RRID:SCR_002865)Results from OddPub: We did not detect open data. We also did not detect open code. Researchers are encouraged to share open data when possible (see Nature blog).
Results from LimitationRecognizer: We detected the following sentences addressing limitations in the study:The majority of patients had specific documentation of difficulty with usual activity and/or work due to functional limitation, with only 26.5% demonstrating a return to baseline health. We found, however, that most patients had an improving symptom course in the 6th week of symptoms. In this cohort, the majority of patients sought further evaluation for their symptoms, with only one patient identified to have a non-COVID-19 alternate diagnosis. Importantly, in patients evaluated for persistent symptoms, a contributing atopic diagnosis or chronic lung disease was often suspected, which lead to specific directed treatments. This possible association is also suggested by comparison of comorbidities between the prolonged symptom group and the overall VOMC cohort (table 2): the incidence of asthma and chronic lung disease (coded at intake visit) were more frequent in the persistent symptom cohort. Anecdotally, we note that many providers report that inhaled bronchodilators and corticosteroids are effective for prolonged COVID-19 symptoms (see video: https://youtu.be/ecPjhdVf41k) and our findings in this report strengthen the case for further research. While respiratory symptoms (cough, dyspnea on exertion, and other) are most common, a variety of symptoms may present across organ systems including neurologic, cardiac, and gastrointestinal. These manifestations merit further investigation as possible evidence of organ-specific dysfunction caused by “mild” COVID-19 in outpatients.
Results from TrialIdentifier: No clinical trial numbers were referenced.
Results from Barzooka: We did not find any issues relating to the usage of bar graphs.
Results from JetFighter: We did not find any issues relating to colormaps.
Results from rtransparent:- Thank you for including a conflict of interest statement. Authors are encouraged to include this statement when submitting to a journal.
- Thank you for including a funding statement. Authors are encouraged to include this statement when submitting to a journal.
- No protocol registration statement was detected.
-
