RETRACTED AND REPLACED: Taste loss as a distinct symptom of COVID-19: a systematic review and meta-analysis
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Abstract
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SciScore for 10.1101/2021.10.09.21264771: (What is this?)
Please note, not all rigor criteria are appropriate for all manuscripts.
Table 1: Rigor
Ethics not detected. Sex as a biological variable We also extracted demographic characteristics of each study, including the population mean and/or median age, sex (expressed as percentage of males in the population), and country of origin (for the geographic distribution of the study populations, see Supplementary Figure 1 (S1)). Randomization not detected. Blinding not detected. Power Analysis not detected. Table 2: Resources
Software and Algorithms Sentences Resources Articles were selected via searches on Pubmed/Medline and Google Scholar, using the keyword “COVID-19” with “taste”, “smell”, and/or “olfaction”, as well as “gustatory”. Pubmed/Medlinesuggested: NoneGoogle Scholarsuggested: (Google Scholar, …SciScore for 10.1101/2021.10.09.21264771: (What is this?)
Please note, not all rigor criteria are appropriate for all manuscripts.
Table 1: Rigor
Ethics not detected. Sex as a biological variable We also extracted demographic characteristics of each study, including the population mean and/or median age, sex (expressed as percentage of males in the population), and country of origin (for the geographic distribution of the study populations, see Supplementary Figure 1 (S1)). Randomization not detected. Blinding not detected. Power Analysis not detected. Table 2: Resources
Software and Algorithms Sentences Resources Articles were selected via searches on Pubmed/Medline and Google Scholar, using the keyword “COVID-19” with “taste”, “smell”, and/or “olfaction”, as well as “gustatory”. Pubmed/Medlinesuggested: NoneGoogle Scholarsuggested: (Google Scholar, RRID:SCR_008878)Results from OddPub: Thank you for sharing your code and data.
Results from LimitationRecognizer: We detected the following sentences addressing limitations in the study:Limitations and Future Research: In many of the included articles, clinicians and researchers collected self-reported taste loss information in tandem with smell loss (e.g., participants responding yes to “Loss of taste and smell” on a symptom screener), which can confound the results. Therefore, we explored any differences in how taste loss was collected, reflecting how it was reported in the articles (e.g., “smell and taste” vs. “taste only”), and found no significant impact on the prevalence rate (see Supplementary Materials S3). This result indicates that taste loss is a common and pervasive symptom of COVID-19. Additionally, far more articles in this meta-analysis used self-report tests (n = 223) than direct tests (n = 18). This disparity may have prevented us from capturing significant differences between the two methods. Nearly all of the articles included in this meta-analysis were nonspecific to different tastes, instead summarizing scores across multiple stimuli (e.g., sweet and salty) and reporting taste loss as a whole (though in one study participants self-reported taste-specific dysfunction: salt taste loss, 29.3%; sweet taste, 25.9%; general taste, 34.5% [El Kady et al., 2021]). However, specific taste sensitivities can be difficult to assess via self-report. Members of the general population, untrained in chemosensory science, may have difficulties identifying whether or not they truly lost a specific taste. Therefore, it is important to use direct measures to...
Results from TrialIdentifier: No clinical trial numbers were referenced.
Results from Barzooka: We did not find any issues relating to the usage of bar graphs.
Results from JetFighter: We did not find any issues relating to colormaps.
Results from rtransparent:- Thank you for including a conflict of interest statement. Authors are encouraged to include this statement when submitting to a journal.
- Thank you for including a funding statement. Authors are encouraged to include this statement when submitting to a journal.
- No protocol registration statement was detected.
Results from scite Reference Check: We found no unreliable references.
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