Evaluation of the effects of repeated disinfection on medical exam gloves: Part 1. Changes in physical integrity
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Abstract
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SciScore for 10.1101/2021.05.31.21258129: (What is this?)
Please note, not all rigor criteria are appropriate for all manuscripts.
Table 1: Rigor
Ethics not detected. Sex as a biological variable not detected. Randomization not detected. Blinding not detected. Power Analysis Statistical Analysis: The sample size was based on a non-inferiority trial design, comparing a glove exposed to a sanitizing procedure to an unexposed control glove. Table 2: Resources
No key resources detected.
Results from OddPub: We did not detect open data. We also did not detect open code. Researchers are encouraged to share open data when possible (see Nature blog).
Results from LimitationRecognizer: We detected the following sentences addressing limitations in the study:The study has some limitations. The gloves purchased in India were sourced from a single company, so they …
SciScore for 10.1101/2021.05.31.21258129: (What is this?)
Please note, not all rigor criteria are appropriate for all manuscripts.
Table 1: Rigor
Ethics not detected. Sex as a biological variable not detected. Randomization not detected. Blinding not detected. Power Analysis Statistical Analysis: The sample size was based on a non-inferiority trial design, comparing a glove exposed to a sanitizing procedure to an unexposed control glove. Table 2: Resources
No key resources detected.
Results from OddPub: We did not detect open data. We also did not detect open code. Researchers are encouraged to share open data when possible (see Nature blog).
Results from LimitationRecognizer: We detected the following sentences addressing limitations in the study:The study has some limitations. The gloves purchased in India were sourced from a single company, so they may not be representative of the variety available for purchase on the market. Additionally, since the recommended CDC and WHO protocols for disinfection of gloves/hand hygiene were strictly followed, the resulting exposures may have been longer or more physically abrasive to the gloves than real-life hand hygiene behaviors, which may be performed for less time or with less intensity than recommended. Finally, although the non-inferiority margin was selected based on the FDA guidance, evidence in the literature, and expert opinion, there is no standard accepted margin for increased risk of tears and leaks in medical examination gloves. In conclusion, wide variability was observed in the effect of disinfecting latex and nitrile medical examination gloves with repeated applications of ABHR, dilute bleach solution, and soap and water. The findings support the recommendation of glove disinfection with ten applications of dilute bleach solution in settings with severe PPE shortages. ABHR and soap and water had mixed effects depending on the glove type. Given this variability, appropriate guidance on extended glove use for HCWs may require testing to evaluate whether locally available glove options are compatible with locally available disinfectants. This study provides glove testing protocols that could reasonably be done by non-experts in a low-resource setting. Extended use ...
Results from TrialIdentifier: No clinical trial numbers were referenced.
Results from Barzooka: We did not find any issues relating to the usage of bar graphs.
Results from JetFighter: We did not find any issues relating to colormaps.
Results from rtransparent:- Thank you for including a conflict of interest statement. Authors are encouraged to include this statement when submitting to a journal.
- Thank you for including a funding statement. Authors are encouraged to include this statement when submitting to a journal.
- No protocol registration statement was detected.
Results from scite Reference Check: We found no unreliable references.
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