Structural genetics of circulating variants affecting the SARS-CoV-2 spike/human ACE2 complex
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SciScore for 10.1101/2020.09.09.289074: (What is this?)
Please note, not all rigor criteria are appropriate for all manuscripts.
Table 1: Rigor
NIH rigor criteria are not applicable to paper type.Table 2: Resources
Software and Algorithms Sentences Resources In order to prevent unrealistic distortion of the Spike-ACE2 complex, due the usage of structures not covering the full length of the interacting proteins, the mutations effect has been qualitatively estimated by means of the mutagenesis tool implemented in PyMol software (48). PyMolsuggested: (PyMOL, RRID:SCR_000305)Results from OddPub: Thank you for sharing your data.
Results from LimitationRecognizer: An explicit section about the limitations of the techniques employed in this study was not found. We encourage authors to address study limitations.Results from TrialIdentifier: No clinical …
SciScore for 10.1101/2020.09.09.289074: (What is this?)
Please note, not all rigor criteria are appropriate for all manuscripts.
Table 1: Rigor
NIH rigor criteria are not applicable to paper type.Table 2: Resources
Software and Algorithms Sentences Resources In order to prevent unrealistic distortion of the Spike-ACE2 complex, due the usage of structures not covering the full length of the interacting proteins, the mutations effect has been qualitatively estimated by means of the mutagenesis tool implemented in PyMol software (48). PyMolsuggested: (PyMOL, RRID:SCR_000305)Results from OddPub: Thank you for sharing your data.
Results from LimitationRecognizer: An explicit section about the limitations of the techniques employed in this study was not found. We encourage authors to address study limitations.Results from TrialIdentifier: No clinical trial numbers were referenced.
Results from Barzooka: We did not find any issues relating to the usage of bar graphs.
Results from JetFighter: We did not find any issues relating to colormaps.
Results from rtransparent:- Thank you for including a conflict of interest statement. Authors are encouraged to include this statement when submitting to a journal.
- Thank you for including a funding statement. Authors are encouraged to include this statement when submitting to a journal.
- No protocol registration statement was detected.
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