Muscle strength explains the protective effect of physical activity against COVID-19 hospitalization among adults aged 50 years and older

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Abstract

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  1. SciScore for 10.1101/2021.02.25.21252451: (What is this?)

    Please note, not all rigor criteria are appropriate for all manuscripts.

    Table 1: Rigor

    Institutional Review Board StatementIRB: SHARE (waves 1-4) was approved by the Ethics Committee of the University of Mannheim.
    Randomizationnot detected.
    Blindingnot detected.
    Power Analysisnot detected.
    Sex as a biological variablenot detected.

    Table 2: Resources

    No key resources detected.


    Results from OddPub: We did not detect open data. We also did not detect open code. Researchers are encouraged to share open data when possible (see Nature blog).


    Results from LimitationRecognizer: We detected the following sentences addressing limitations in the study:
    However, this work also presents some limitations. First, low-to-moderate and vigorous physical activity were self-reported, which may have reduced measurement validity. Second, because physical activity and other risks factors could have been assessed at a same time, we cannot infer a causal relationship between these variables (i.e., physical activity can affect certain chronic conditions, and vice versa). Third, our study focused on the potential protective role of usual or long-term physical activity patterns but did not investigate how acute level of physical activity at the time of the potential infection can also influence odds of hospitalization. Future studies should determine whether current levels of physical activity are more closely related to risks for COVID-19 hospitalization, than usual physical activity. Fourth, established risk factors for COVID-19 hospitalization were self-reported, which may have decreased the validity of these measures. Similarly, because the latest assessment of these risk factors was at a minimum of two years before patients’ potential infection to COVID-19, some individuals may have contracted the diseases during this period, thereby resulting in a misclassification bias. These latter limitations may explain the non-significant associations between these established risk factors and odds of COVID-19 hospitalization. Future larger-scale studies are needed to examine whether the associations of physical activity with severe COVID-19 may ...

    Results from TrialIdentifier: No clinical trial numbers were referenced.


    Results from Barzooka: We did not find any issues relating to the usage of bar graphs.


    Results from JetFighter: We did not find any issues relating to colormaps.


    Results from rtransparent:
    • Thank you for including a conflict of interest statement. Authors are encouraged to include this statement when submitting to a journal.
    • Thank you for including a funding statement. Authors are encouraged to include this statement when submitting to a journal.
    • No protocol registration statement was detected.

    About SciScore

    SciScore is an automated tool that is designed to assist expert reviewers by finding and presenting formulaic information scattered throughout a paper in a standard, easy to digest format. SciScore checks for the presence and correctness of RRIDs (research resource identifiers), and for rigor criteria such as sex and investigator blinding. For details on the theoretical underpinning of rigor criteria and the tools shown here, including references cited, please follow this link.