Protection against the Omicron Variant from Previous SARS-CoV-2 Infection

  1. Heba N. Altarawneh
  2. Hiam Chemaitelly
  3. Mohammad R. Hasan
  4. Houssein H. Ayoub
  5. Suelen Qassim
  6. Sawsan AlMukdad
  7. Peter Coyle
  8. Hadi M. Yassine
  9. Hebah A. Al-Khatib
  10. Fatiha M. Benslimane
  11. Zaina Al-Kanaani
  12. Einas Al-Kuwari
  13. Andrew Jeremijenko
  14. Anvar H. Kaleeckal
  15. Ali N. Latif
  16. Riyazuddin M. Shaik
  17. Hanan F. Abdul-Rahim
  18. Gheyath K. Nasrallah
  19. Mohamed G. Al-Kuwari
  20. Adeel A. Butt
  21. Hamad E. Al-Romaihi
  22. Mohamed H. Al-Thani
  23. Abdullatif Al-Khal
  24. Roberto Bertollini
  25. Patrick Tang
  26. Laith J. Abu-Raddad

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Abstract

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  1. Version published to 10.1056/nejmc2200133
  2. ScreenIT

    SciScore for 10.1101/2022.01.05.22268782: (What is this?)

    Please note, not all rigor criteria are appropriate for all manuscripts.

    Table 1: Rigor

    EthicsIRB: The study was approved by the Hamad Medical Corporation and Weill Cornell Medicine-Qatar Institutional Review Boards with a waiver of informed consent.
    Consent: The study was approved by the Hamad Medical Corporation and Weill Cornell Medicine-Qatar Institutional Review Boards with a waiver of informed consent.
    Sex as a biological variablenot detected.
    Randomizationnot detected.
    Blindingnot detected.
    Power Analysisnot detected.
    Cell Line AuthenticationAuthentication: Effectiveness of prior infection in preventing reinfection (PES) was defined as the proportional reduction in susceptibility to infection among those with prior infection versus those without.6,7 The test-negative methodology was recently investigated and validated for the specific derivation of rigorous and robust estimates for SARS-CoV-2 PES.

    Table 2: Resources

    No key resources detected.

    Results from OddPub: We did not detect open data. We also did not detect open code. Researchers are encouraged to share open data when possible (see Nature blog).

    Results from LimitationRecognizer: We detected the following sentences addressing limitations in the study:
    Notwithstanding these limitations, consistent findings were reached in both the main and sensitivity analyses. Estimates for the effectiveness of prior infection against reinfection with the Alpha and Beta variants were also consistent and similar to those generated earlier in the same population of Qatar using cohort study designs.1,2

    Results from TrialIdentifier: No clinical trial numbers were referenced.

    Results from Barzooka: We did not find any issues relating to the usage of bar graphs.

    Results from JetFighter: We did not find any issues relating to colormaps.

    Results from rtransparent:
    • Thank you for including a conflict of interest statement. Authors are encouraged to include this statement when submitting to a journal.
    • Thank you for including a funding statement. Authors are encouraged to include this statement when submitting to a journal.
    • No protocol registration statement was detected.

    Results from scite Reference Check: We found no unreliable references.

    About SciScore

    SciScore is an automated tool that is designed to assist expert reviewers by finding and presenting formulaic information scattered throughout a paper in a standard, easy to digest format. SciScore checks for the presence and correctness of RRIDs (research resource identifiers), and for rigor criteria such as sex and investigator blinding. For details on the theoretical underpinning of rigor criteria and the tools shown here, including references cited, please follow this link.

  3. Version published to 10.1101/2022.01.05.22268782v1 on medRxiv