Controlling the SARS-CoV-2 spike glycoprotein conformation
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SciScore for 10.1101/2020.05.18.102087: (What is this?)
Please note, not all rigor criteria are appropriate for all manuscripts.
Table 1: Rigor
NIH rigor criteria are not applicable to paper type.Table 2: Resources
Experimental Models: Cell Lines Sentences Resources This work was supported by UM1 AI100645 ( B.F . H) , the Duke Center for HIV/AIDS Vaccine ImmunologyImmunogen Discovery , and UM1 AI44371 ( B.F . H . ) , the Duke Consortium for HIV/AIDS Vaccine Development , Division of AIDS , NIAID , NIH; Duke University Center for AIDS Research ( CFAR); bioRxiv UM1 AI44371suggested: NoneSoftware and Algorithms Sentences Resources Finally, the disposition of the CD to the inner portion of S2 measured as an angle between a vector connected to an interior S2 β-sheet motif and the … SciScore for 10.1101/2020.05.18.102087: (What is this?)
Please note, not all rigor criteria are appropriate for all manuscripts.
Table 1: Rigor
NIH rigor criteria are not applicable to paper type.Table 2: Resources
Experimental Models: Cell Lines Sentences Resources This work was supported by UM1 AI100645 ( B.F . H) , the Duke Center for HIV/AIDS Vaccine ImmunologyImmunogen Discovery , and UM1 AI44371 ( B.F . H . ) , the Duke Consortium for HIV/AIDS Vaccine Development , Division of AIDS , NIAID , NIH; Duke University Center for AIDS Research ( CFAR); bioRxiv UM1 AI44371suggested: NoneSoftware and Algorithms Sentences Resources Finally, the disposition of the CD to the inner portion of S2 measured as an angle between a vector connected to an interior S2 β-sheet motif and the vector connecting bioRxiv preprint doi: https://doi.org/10.1101/2020.05.18.102087. this version posted May 18, 2020. bioRxivsuggested: (bioRxiv, SCR_003933)Consistent with what was observed in the NSEM analysis, after multiple rounds of 2D and 3D-classification to remove junk particles and broken and/or misfolded spikes, we found a population of ‘down’ state spike in the rS2d dataset through ab initio classification in cryoSparc. cryoSparcsuggested: (cryoSPARC, SCR_016501)Coordinates were then fit manually in Coot45 followed by iterative refinement using Phenix46 real space refinement and subsequent manual coordinate fitting in Coot. Cootsuggested: (Coot, SCR_014222)Structure and map analysis were performed using PyMol and Chimera. bioRxiv preprint doi: https://doi.org/10.1101/2020.05.18.102087. this version posted May 18, 2020. PyMolsuggested: (PyMOL, SCR_000305)Results from OddPub: We did not find a statement about open data. We also did not find a statement about open code. Researchers are encouraged to share open data when possible (see Nature blog).
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