Convalescent plasma treatment of severe COVID-19: a propensity score–matched control study
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SciScore for 10.1101/2020.05.20.20102236: (What is this?)
Please note, not all rigor criteria are appropriate for all manuscripts.
Table 1: Rigor
Institutional Review Board Statement Consent: Four patients improved and 2 patients withdrew consent prior to receipt of plasma, leaving 39 evaluable patients who received COVID-19 convalescent plasma.
IRB: Both treatment and research were performed with the oversight of the Icahn School of Medicine at Mount Sinai Institutional Review Board (IRB).Randomization not detected. Blinding not detected. Power Analysis not detected. Sex as a biological variable not detected. Table 2: Resources
Antibodies Sentences Resources Convalescent plasma transfusion: Convalescent plasma donors were screened for SARS-CoV-2 antibody titers by a two-step Spike protein-directed ELISA.20,21 Donors with anti-spike antibody titers … SciScore for 10.1101/2020.05.20.20102236: (What is this?)
Please note, not all rigor criteria are appropriate for all manuscripts.
Table 1: Rigor
Institutional Review Board Statement Consent: Four patients improved and 2 patients withdrew consent prior to receipt of plasma, leaving 39 evaluable patients who received COVID-19 convalescent plasma.
IRB: Both treatment and research were performed with the oversight of the Icahn School of Medicine at Mount Sinai Institutional Review Board (IRB).Randomization not detected. Blinding not detected. Power Analysis not detected. Sex as a biological variable not detected. Table 2: Resources
Antibodies Sentences Resources Convalescent plasma transfusion: Convalescent plasma donors were screened for SARS-CoV-2 antibody titers by a two-step Spike protein-directed ELISA.20,21 Donors with anti-spike antibody titers ≥1:320 were referred for blood collection at the New York Blood Center, which performed the plasmapheresis and then returned convalescent plasma units to The Mount Sinai Hospital. anti-spikesuggested: NoneSoftware and Algorithms Sentences Resources Analysis was performed using SAS 9.4 (SAS Institute Inc., Cary, NC). SAS Institutesuggested: (Statistical Analysis System, RRID:SCR_008567)Results from OddPub: We did not detect open data. We also did not detect open code. Researchers are encouraged to share open data when possible (see Nature blog).
Results from LimitationRecognizer: An explicit section about the limitations of the techniques employed in this study was not found. We encourage authors to address study limitations.Results from TrialIdentifier: No clinical trial numbers were referenced.
Results from Barzooka: We did not find any issues relating to the usage of bar graphs.
Results from JetFighter: We did not find any issues relating to colormaps.
Results from rtransparent:- Thank you for including a conflict of interest statement. Authors are encouraged to include this statement when submitting to a journal.
- Thank you for including a funding statement. Authors are encouraged to include this statement when submitting to a journal.
- No protocol registration statement was detected.
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