Broadly inhibitory antibodies to severe malaria virulence proteins

  1. Raphael A. Reyes
  2. Sai Sundar Rajan Raghavan
  3. Nicholas K. Hurlburt
  4. Viola Introini
  5. Sebastiaan Bol
  6. Ikhlaq Hussain Kana
  7. Rasmus W. Jensen
  8. Elizabeth Martinez-Scholze
  9. María Gestal-Mato
  10. Borja López-Gutiérrez
  11. Silvia Sanz
  12. Cristina Bancells
  13. Monica Lisa Fernández-Quintero
  14. Johannes R. Loeffler
  15. James Alexander Ferguson
  16. Wen-Hsin Lee
  17. Greg Michael Martin
  18. Thor G. Theander
  19. John P. A. Lusingu
  20. Daniel T. R. Minja
  21. Isaac Ssewanyana
  22. Margaret E. Feeney
  23. Bryan Greenhouse
  24. Andrew B. Ward
  25. Maria Bernabeu
  26. Marie Pancera
  27. Louise Turner
  28. Evelien M. Bunnik
  29. Thomas Lavstsen

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Abstract

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  1. Version published to 10.1038/s41586-024-08220-3
  2. Rapid Reviews Infectious Diseases

    Takafumi Tsuobi

    Review 2: "Broadly Inhibitory Antibodies against Severe Malaria Virulence Proteins"

    The reviewers found the study compelling, providing strong evidence for the existence of broadly inhibitory human antibodies that can recognize and neutralize the diverse range of PfEMP1 variants from Plasmodium falciparum involved in severe malaria pathogenesis.

  3. Rapid Reviews Infectious Diseases

    Brandon Wilder

    Review 1: "Broadly Inhibitory Antibodies against Severe Malaria Virulence Proteins"

    The reviewers found the study compelling, providing strong evidence for the existence of broadly inhibitory human antibodies that can recognize and neutralize the diverse range of PfEMP1 variants from Plasmodium falciparum involved in severe malaria pathogenesis.

  5. Version published to 10.1101/2024.01.25.577124 on bioRxiv