Assessing transmissibility of SARS-CoV-2 lineage B.1.1.7 in England

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Abstract

No abstract available

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  1. SciScore for 10.1101/2020.12.30.20249034: (What is this?)

    Please note, not all rigor criteria are appropriate for all manuscripts.

    Table 1: Rigor

    Institutional Review Board Statementnot detected.
    Randomizationnot detected.
    Blindingnot detected.
    Power Analysisnot detected.
    Sex as a biological variablenot detected.

    Table 2: Resources

    No key resources detected.


    Results from OddPub: Thank you for sharing your code and data.


    Results from LimitationRecognizer: We detected the following sentences addressing limitations in the study:
    There are a number of limitations to our analysis. The genomic and epidemiological data analysed was collected as part of routine surveillance, and thus may not be an entirely representative sample of SARS-CoV-2 infections in England over the time period considered. We also focussed on relatively simple, data-driven analyses using relatively simple models making parsimonious assumptions, rather than, for instance, attempting to model the long-term transmission dynamics of VOC and non-VOC lineages more mechanistically. We also did not attempt to explicitly model the spatiotemporal correlation intrinsic in infectious disease data, especially when considering the spread of a new variant from a point source. Doing so is an important priority for future work, but will require explicit incorporation of data on population movement patterns. Early versions of our analyses informed the UK government policy response to this VOC and that of other countries. The substantial transmission advantage we have estimated the VOC to have over prior viral lineages poses major challenges for ongoing control of COVID-19 in the UK and elsewhere in the coming months. Social distancing measures will need to be more stringent than they would have otherwise. A particular concern is whether it will be possible to maintain control over transmission while allowing schools to reopen in January 2021. These policy questions will be informed by the ongoing urgent epidemiological investigation into this variant...

    Results from TrialIdentifier: No clinical trial numbers were referenced.


    Results from Barzooka: We did not find any issues relating to the usage of bar graphs.


    Results from JetFighter: We did not find any issues relating to colormaps.


    Results from rtransparent:
    • Thank you for including a conflict of interest statement. Authors are encouraged to include this statement when submitting to a journal.
    • Thank you for including a funding statement. Authors are encouraged to include this statement when submitting to a journal.
    • No protocol registration statement was detected.

    About SciScore

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