Repeated cross-sectional sero-monitoring of SARS-CoV-2 in New York City
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SciScore for 10.1101/2020.06.28.20142190: (What is this?)
Please note, not all rigor criteria are appropriate for all manuscripts.
Table 1: Rigor
Institutional Review Board Statement IRB: The collection and testing of plasma was approved by the Mount Sinai Hospital Institutional Review Board, protocol HS# 20-03253 Randomization not detected. Blinding Plasma samples were chosen in a blinded and unbiased manner. Power Analysis not detected. Sex as a biological variable not detected. Table 2: Resources
Antibodies Sentences Resources After 2 h the plates were washed three times with PBS-T and 50 µL anti-human IgG (Fab-specific) horseradish peroxidase antibody (HRP, produced in goat; Sigma, #A0293 anti-human IgGsuggested: (Sigma-Aldrich Cat# A0293, RRID:AB_257875)Software and Algorithms Sentences Resources https://www.beiresources.org/). https://www.beiresources.…SciScore for 10.1101/2020.06.28.20142190: (What is this?)
Please note, not all rigor criteria are appropriate for all manuscripts.
Table 1: Rigor
Institutional Review Board Statement IRB: The collection and testing of plasma was approved by the Mount Sinai Hospital Institutional Review Board, protocol HS# 20-03253 Randomization not detected. Blinding Plasma samples were chosen in a blinded and unbiased manner. Power Analysis not detected. Sex as a biological variable not detected. Table 2: Resources
Antibodies Sentences Resources After 2 h the plates were washed three times with PBS-T and 50 µL anti-human IgG (Fab-specific) horseradish peroxidase antibody (HRP, produced in goat; Sigma, #A0293 anti-human IgGsuggested: (Sigma-Aldrich Cat# A0293, RRID:AB_257875)Software and Algorithms Sentences Resources https://www.beiresources.org/). https://www.beiresources.org/suggested: (BEI Resource Repository, RRID:SCR_013698)The data were analyzed in Microsoft Excel and GraphPad Prism 7. Microsoft Excelsuggested: (Microsoft Excel, RRID:SCR_016137)GraphPad Prismsuggested: (GraphPad Prism, RRID:SCR_002798)Results from OddPub: We did not detect open data. We also did not detect open code. Researchers are encouraged to share open data when possible (see Nature blog).
Results from LimitationRecognizer: An explicit section about the limitations of the techniques employed in this study was not found. We encourage authors to address study limitations.Results from TrialIdentifier: No clinical trial numbers were referenced.
Results from Barzooka: We did not find any issues relating to the usage of bar graphs.
Results from JetFighter: We did not find any issues relating to colormaps.
Results from rtransparent:- Thank you for including a conflict of interest statement. Authors are encouraged to include this statement when submitting to a journal.
- Thank you for including a funding statement. Authors are encouraged to include this statement when submitting to a journal.
- No protocol registration statement was detected.
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SciScore for 10.1101/2020.06.28.20142190: (What is this?)
Please note, not all rigor criteria are appropriate for all manuscripts.
Table 1: Rigor
Institutional Review Board Statement The collection and testing of plasma was approved by the Mount Sinai Hospital Institutional Review Board, protocol HS# 20-03253. Randomization not detected. Blinding Plasma samples were chosen in a blinded and unbiased manner. Power Analysis not detected. Sex as a biological variable The sentinel group comprised 43.6% females while the screening group included 65.8% females (Table 1). Table 2: Resources
Antibodies Sentences Resources Several serological assays for measuring antibodies to SARS-CoV-2 have been developed (5). SARS-CoV-2suggested: NoneAfter 2 h the plates were washed three times with … SciScore for 10.1101/2020.06.28.20142190: (What is this?)
Please note, not all rigor criteria are appropriate for all manuscripts.
Table 1: Rigor
Institutional Review Board Statement The collection and testing of plasma was approved by the Mount Sinai Hospital Institutional Review Board, protocol HS# 20-03253. Randomization not detected. Blinding Plasma samples were chosen in a blinded and unbiased manner. Power Analysis not detected. Sex as a biological variable The sentinel group comprised 43.6% females while the screening group included 65.8% females (Table 1). Table 2: Resources
Antibodies Sentences Resources Several serological assays for measuring antibodies to SARS-CoV-2 have been developed (5). SARS-CoV-2suggested: NoneAfter 2 h the plates were washed three times with PBS-T and 50 µL antihuman IgG (Fab-specific) horseradish peroxidase antibody (HRP, produced in goat; Sigma, #A0293) diluted 1:3,000 in PBS-T containing 1% milk powder was added to all wells and incubated for 1 h at room temperature. antihuman IgGsuggested: (GeneTex Cat# GTX28798, AB_374523)Software and Algorithms Sentences Resources The expression plasmids are available at BEI Resources Repository (https://www.beiresources.org/). https://www.beiresources.org/suggested: (BEI Resource Repository, SCR_013698)The data were analyzed in Microsoft Excel and GraphPad Prism 7. Microsoft Excelsuggested: (Microsoft Excel, SCR_016137)<div style="margin-bottom:8px"> <div><b>GraphPad Prism</b></div> <div>suggested: (GraphPad Prism, <a href="https://scicrunch.org/resources/Any/search?q=SCR_002798">SCR_002798</a>)</div> </div> </td></tr></table>Results from LimitationRecognizer: An explicit section about the limitations of the techniques employed in this study was not found. We encourage authors to address study limitations.
Results from OddPub: We did not find a statement about open data. We also did not find a statement about open code. Researchers are encouraged to share open data when possible (see Nature blog).
About SciScore
SciScore is an automated tool that is designed to assist expert reviewers by finding and presenting formulaic information scattered throughout a paper in a standard, easy to digest format. SciScore is not a substitute for expert review. SciScore checks for the presence and correctness of RRIDs (research resource identifiers) in the manuscript, and detects sentences that appear to be missing RRIDs. SciScore also checks to make sure that rigor criteria are addressed by authors. It does this by detecting sentences that discuss criteria such as blinding or power analysis. SciScore does not guarantee that the rigor criteria that it detects are appropriate for the particular study. Instead it assists authors, editors, and reviewers by drawing attention to sections of the manuscript that contain or should contain various rigor criteria and key resources. For details on the results shown here, including references cited, please follow this link.
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