Structure of Mpro from SARS-CoV-2 and discovery of its inhibitors
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SciScore for 10.1101/2020.02.26.964882: (What is this?)
Please note, not all rigor criteria are appropriate for all manuscripts.
Table 1: Rigor
Institutional Review Board Statement not detected. Randomization not detected. Blinding not detected. Power Analysis not detected. Sex as a biological variable not detected. Cell Line Authentication not detected. Table 2: Resources
Experimental Models: Cell Lines Sentences Resources As shown in Fig. 4a, quantitative real-time RT-PCR (qRT-PCR) demonstrated that ebselen and N3 showed the strongest antiviral effects among them at a concentration of 10 μM treatment in COVID19 virus infected Vero cells. Verosuggested: CLS Cat# 605372/p622_VERO, CVCL_0059Results from OddPub: Thank you for sharing your data.
About SciScore
SciScore is an …
SciScore for 10.1101/2020.02.26.964882: (What is this?)
Please note, not all rigor criteria are appropriate for all manuscripts.
Table 1: Rigor
Institutional Review Board Statement not detected. Randomization not detected. Blinding not detected. Power Analysis not detected. Sex as a biological variable not detected. Cell Line Authentication not detected. Table 2: Resources
Experimental Models: Cell Lines Sentences Resources As shown in Fig. 4a, quantitative real-time RT-PCR (qRT-PCR) demonstrated that ebselen and N3 showed the strongest antiviral effects among them at a concentration of 10 μM treatment in COVID19 virus infected Vero cells. Verosuggested: CLS Cat# 605372/p622_VERO, CVCL_0059Results from OddPub: Thank you for sharing your data.
About SciScore
SciScore is an automated tool that is designed to assist expert reviewers by finding and presenting formulaic information scattered throughout a paper in a standard, easy to digest format. SciScore is not a substitute for expert review. SciScore checks for the presence and correctness of RRIDs (research resource identifiers) in the manuscript, and detects sentences that appear to be missing RRIDs. SciScore also checks to make sure that rigor criteria are addressed by authors. It does this by detecting sentences that discuss criteria such as blinding or power analysis. SciScore does not guarantee that the rigor criteria that it detects are appropriate for the particular study. Instead it assists authors, editors, and reviewers by drawing attention to sections of the manuscript that contain or should contain various rigor criteria and key resources. For details on the results shown here, including references cited, please follow this link.
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