Epidemiological and clinical characteristics of the COVID-19 epidemic in Brazil
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SciScore for 10.1101/2020.04.25.20077396: (What is this?)
Please note, not all rigor criteria are appropriate for all manuscripts.
Table 1: Rigor
Institutional Review Board Statement not detected. Randomization not detected. Blinding not detected. Power Analysis not detected. Sex as a biological variable not detected. Table 2: Resources
Software and Algorithms Sentences Resources Individual-level data on notified cases from Brazil: To investigate individual-level diagnostic, demographic, self-reported travel history, place of residence and likely place of infection, differential diagnosis for other respiratory pathogens, as well as clinical details, including comorbidities, we collected case data notified to the REDCap database8 from February 25 to March 25, 2020. REDCapsuggested: (REDCap, RRID:SCR_003445)Results from OddPub: We did not detect open …
SciScore for 10.1101/2020.04.25.20077396: (What is this?)
Please note, not all rigor criteria are appropriate for all manuscripts.
Table 1: Rigor
Institutional Review Board Statement not detected. Randomization not detected. Blinding not detected. Power Analysis not detected. Sex as a biological variable not detected. Table 2: Resources
Software and Algorithms Sentences Resources Individual-level data on notified cases from Brazil: To investigate individual-level diagnostic, demographic, self-reported travel history, place of residence and likely place of infection, differential diagnosis for other respiratory pathogens, as well as clinical details, including comorbidities, we collected case data notified to the REDCap database8 from February 25 to March 25, 2020. REDCapsuggested: (REDCap, RRID:SCR_003445)Results from OddPub: We did not detect open data. We also did not detect open code. Researchers are encouraged to share open data when possible (see Nature blog).
Results from LimitationRecognizer: We detected the following sentences addressing limitations in the study:We identified several limitations in our study. First, detailed individual-level data was only available for the first month of the epidemic in Brazil. Moreover, several cases had incomplete documentation, such as hospitalization date, mechanical ventilation, and travel history. Real-time aggregated data and open-access open line lists have the potential to provide real-time insights into transmissibility14. Secondly, our retrospective study has focused predominantly on symptomatic patients (92%) that presented themselves to health services for testing. Therefore, we cannot describe the full spectrum of disease. Population-based serologic surveys are urgently needed to properly determine the asymptomatic and oligosymptomatic fraction. Finally, many patients remained hospitalized when the dataset was extracted, and, we were unable to estimate clinical outcomes given the long duration of infection. Together with changes in surveillance guidelines, socioeconomic bias in testing suggests that the number of confirmed case counts may substantially underestimate the true number of cases in the population. Additional reasons for underreporting include (i) a significant proportion of asymptomatic infections15, (ii) people with mild and even moderate disease are unlikely to present to health services for testing, (iii) limited testing capacity in public health service in Brazil in face of the large number of cases due to delays in importing reagents and kits used in molecular testing. ...
Results from TrialIdentifier: No clinical trial numbers were referenced.
Results from Barzooka: We did not find any issues relating to the usage of bar graphs.
Results from JetFighter: We did not find any issues relating to colormaps.
Results from rtransparent:- Thank you for including a conflict of interest statement. Authors are encouraged to include this statement when submitting to a journal.
- Thank you for including a funding statement. Authors are encouraged to include this statement when submitting to a journal.
- No protocol registration statement was detected.
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