A broad-spectrum antibiotic targets multiple-drug-resistant bacteria with dual binding targets and no detectable resistance

  1. Wenyan He
  2. Xueting Huan
  3. Yinchuan Li
  4. Qisen Deng
  5. Tao Chen
  6. Wen Xiao
  7. Yijun Chen
  8. Lingman Ma
  9. Nan Liu
  10. Zhuo Shang
  11. Zongqiang Wang

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Abstract

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  1. Version published to 10.1038/s41467-025-62407-4
  2. Rapid Reviews Infectious Diseases

    César de la Fuente

    Review 1: "A Novel Broad-spectrum Antibiotic Targets Multiple-drug-resistant Bacteria with Dual Binding Targets and No Detectable Resistance"

    The reviewer suggested further structural and biophysical characterization to address the mechanism of action, as well as longer passaging to closer mimic clinical conditions upon which resistance occurs would strengthen the preprint.

  3. Rapid Reviews Infectious Diseases

    César de la Fuente

    Review of "A Novel Broad-spectrum Antibiotic Targets Multiple-drug-resistant Bacteria with Dual Binding Targets and No Detectable Resistance"

    Reviewer(s): C de la Fuente (University of Pennsylvania) | 📘📘📘📘📘

  4. Version published to 10.1101/2025.01.11.632532 on bioRxiv