Mouthrinses and SARS-CoV-2 viral load in saliva: a living systematic review
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SciScore for 10.1101/2021.03.23.21254214: (What is this?)
Please note, not all rigor criteria are appropriate for all manuscripts.
Table 1: Rigor
Institutional Review Board Statement not detected. Randomization not detected. Blinding not detected. Power Analysis not detected. Sex as a biological variable not detected. Table 2: Resources
No key resources detected.
Results from OddPub: We did not detect open data. We also did not detect open code. Researchers are encouraged to share open data when possible (see Nature blog).
Results from LimitationRecognizer: We detected the following sentences addressing limitations in the study:One of the limitations of the study is that due to the low quality of the studies, small sample size, as well as the heterogeneity reported in terms of follow-up periods, and reporting of viral load measurement, the calculation …
SciScore for 10.1101/2021.03.23.21254214: (What is this?)
Please note, not all rigor criteria are appropriate for all manuscripts.
Table 1: Rigor
Institutional Review Board Statement not detected. Randomization not detected. Blinding not detected. Power Analysis not detected. Sex as a biological variable not detected. Table 2: Resources
No key resources detected.
Results from OddPub: We did not detect open data. We also did not detect open code. Researchers are encouraged to share open data when possible (see Nature blog).
Results from LimitationRecognizer: We detected the following sentences addressing limitations in the study:One of the limitations of the study is that due to the low quality of the studies, small sample size, as well as the heterogeneity reported in terms of follow-up periods, and reporting of viral load measurement, the calculation of a meta-analysis would have very limited utility. However, an extensive bibliographic search has been carried out in seven databases, and the search has also been extended to preprint repositories including medRxiv, and bioRxiv, in order to cover the greatest amount of evidence available on the subject. Likewise, the present study has a living systematic review design in order to perform future updates of this study according to the results of completed or ongoing clinical trials registered in the ClinicalTrials.gov portal. This will enable the adoption of a more conclusive position for or against the use of mouth-rinses in reducing the viral load of SARS-CoV-2 in the saliva of patients with COVID-19. In conclusion, according to the present systematic review, the effect of the use of mouth-rinses on the viral load of SARS-CoV-2 continues to be uncertain. The emission of recommendations by governmental organizations around the world about the use of these mouth-rinses as a preventive measure towards infection by SARS-CoV-2 could generate a false sensation of security among dentists, care staff, and patients, which could subsequently lead to a groundless reduction in the use of known effective measures for the prevention of infection and dissemination ...
Results from TrialIdentifier: No clinical trial numbers were referenced.
Results from Barzooka: We did not find any issues relating to the usage of bar graphs.
Results from JetFighter: We did not find any issues relating to colormaps.
Results from rtransparent:- Thank you for including a conflict of interest statement. Authors are encouraged to include this statement when submitting to a journal.
- Thank you for including a funding statement. Authors are encouraged to include this statement when submitting to a journal.
- No protocol registration statement was detected.
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