Clinical features of coronavirus disease 2019 (COVID-19) in a cohort of patients with disability due to spinal cord injury

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Abstract

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  1. SciScore for 10.1101/2020.04.20.20072918: (What is this?)

    Please note, not all rigor criteria are appropriate for all manuscripts.

    Table 1: Rigor

    Institutional Review Board StatementConsent: All participants provided their informed consent.
    IRB: The guidelines of the declaration of Helsinki were followed in every case and the study design was approved by the local Ethics Committee (Hospital Virgen de la Salud, Toledo, Spain, resolution number 504).
    Randomizationnot detected.
    Blindingnot detected.
    Power Analysisnot detected.
    Sex as a biological variablenot detected.

    Table 2: Resources

    No key resources detected.


    Results from OddPub: We did not detect open data. We also did not detect open code. Researchers are encouraged to share open data when possible (see Nature blog).


    Results from LimitationRecognizer: We detected the following sentences addressing limitations in the study:
    The limitations of this study include the fact that none of the patients admitted to the HNP or their healthcare personnel were interviewed for symptoms of infection or received the SARS-CoV-2 screening test, which therefore may have led to an underestimation of the Covid-19 infection rate in the hospital, especially in those patients who were asymptomatic or who presented mild symptoms. As this is a descriptive case series study, there is no control group, the absence of which is justified given the urgency of pandemic and the lack of previous Covid-19 data among SCI population. Unfortunately, it is likely that our Covid-19 SCI case series will gradually increase until the end of the present pandemic, which will provide us with more clinical data with longer evolution times.

    Results from TrialIdentifier: No clinical trial numbers were referenced.


    Results from Barzooka: We did not find any issues relating to the usage of bar graphs.


    Results from JetFighter: We did not find any issues relating to colormaps.


    Results from rtransparent:
    • Thank you for including a conflict of interest statement. Authors are encouraged to include this statement when submitting to a journal.
    • Thank you for including a funding statement. Authors are encouraged to include this statement when submitting to a journal.
    • No protocol registration statement was detected.

    About SciScore

    SciScore is an automated tool that is designed to assist expert reviewers by finding and presenting formulaic information scattered throughout a paper in a standard, easy to digest format. SciScore checks for the presence and correctness of RRIDs (research resource identifiers), and for rigor criteria such as sex and investigator blinding. For details on the theoretical underpinning of rigor criteria and the tools shown here, including references cited, please follow this link.

  2. SciScore for 10.1101/2020.04.20.20072918: (What is this?)

    Please note, not all rigor criteria are appropriate for all manuscripts.

    Table 1: Rigor

    Institutional Review Board StatementAll participants provided their informed consent .Randomizationnot detected.Blindingnot detected.Power Analysisnot detected.Sex as a biological variableSeveral demographic and clinical factors associated with the more aggressive Covid-19 phenotype have been identified: male gender , age over 60 years and the presence of previous comorbidities such as hypertension , diabetes mellitus , obesity , cardiac ischemic disease , lung disease and immunosuppression5 .

    Table 2: Resources


    Results from OddPub: We did not find a statement about open data. We also did not find a statement about open code. Researchers are encouraged to share open data when possible (see Nature blog).


    About SciScore

    SciScore is an automated tool that is designed to assist expert reviewers by finding and presenting formulaic information scattered throughout a paper in a standard, easy to digest format. SciScore is not a substitute for expert review. SciScore checks for the presence and correctness of RRIDs (research resource identifiers) in the manuscript, and detects sentences that appear to be missing RRIDs. SciScore also checks to make sure that rigor criteria are addressed by authors. It does this by detecting sentences that discuss criteria such as blinding or power analysis. SciScore does not guarantee that the rigor criteria that it detects are appropriate for the particular study. Instead it assists authors, editors, and reviewers by drawing attention to sections of the manuscript that contain or should contain various rigor criteria and key resources. For details on the results shown here, please follow this link.