Upregulated miR-200c is associated with downregulation of the functional receptor for severe acute respiratory syndrome coronavirus 2 ACE2 in individuals with obesity
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SciScore for 10.1101/2021.03.29.21254517: (What is this?)
Please note, not all rigor criteria are appropriate for all manuscripts.
Table 1: Rigor
Institutional Review Board Statement IRB: Participants and sample collection: The Health and Disability Ethics Committee of New Zealand approved the use of samples for this study.
Consent: Informed consent was obtained from each patient for the collection and use of samples in this study, and the study protocol conforms to the ethical guidelines of the 1975 Declaration of Helsinki as reflected in a priori approval by the New Zealand Health and Disability Ethics Committee.Randomization Forty-one female participants for the present study were randomly selected from the 221 female individuals recruited in this study. Blinding not detected. Power Analysis not detected. Sex as a biological variable Forty-one … SciScore for 10.1101/2021.03.29.21254517: (What is this?)
Please note, not all rigor criteria are appropriate for all manuscripts.
Table 1: Rigor
Institutional Review Board Statement IRB: Participants and sample collection: The Health and Disability Ethics Committee of New Zealand approved the use of samples for this study.
Consent: Informed consent was obtained from each patient for the collection and use of samples in this study, and the study protocol conforms to the ethical guidelines of the 1975 Declaration of Helsinki as reflected in a priori approval by the New Zealand Health and Disability Ethics Committee.Randomization Forty-one female participants for the present study were randomly selected from the 221 female individuals recruited in this study. Blinding not detected. Power Analysis not detected. Sex as a biological variable Forty-one female participants for the present study were randomly selected from the 221 female individuals recruited in this study. Table 2: Resources
Software and Algorithms Sentences Resources WEight Regain (POWER) study (Clinical Trials Registry number: ACTRN12612000069853), which was designed to assess the effects of cabergoline on the prevention of weight regain in obese individuals. POWERsuggested: (POWER, RRID:SCR_009057)Statistical analysis: All statistical analyses were performed using GraphPad Prism (version 8). GraphPad Prismsuggested: (GraphPad Prism, RRID:SCR_002798)Results from OddPub: We did not detect open data. We also did not detect open code. Researchers are encouraged to share open data when possible (see Nature blog).
Results from LimitationRecognizer: An explicit section about the limitations of the techniques employed in this study was not found. We encourage authors to address study limitations.Results from TrialIdentifier: No clinical trial numbers were referenced.
Results from Barzooka: We did not find any issues relating to the usage of bar graphs.
Results from JetFighter: We did not find any issues relating to colormaps.
Results from rtransparent:- Thank you for including a conflict of interest statement. Authors are encouraged to include this statement when submitting to a journal.
- Thank you for including a funding statement. Authors are encouraged to include this statement when submitting to a journal.
- No protocol registration statement was detected.
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