Interactions between SARS-CoV-2 N-Protein and α-Synuclein Accelerate Amyloid Formation

Article activity feed

1. Version published to 10.1021/acschemneuro.1c00666

   Dec 3, 2021
2. 

   ScreenIT

   Apr 15, 2021

   SciScore for 10.1101/2021.04.12.439549: (What is this?)

   Please note, not all rigor criteria are appropriate for all manuscripts.

   Table 1: Rigor

   NIH rigor criteria are not applicable to paper type.

   Table 2: Resources

   Experimental Models: Cell Lines
   Sentences	Resources
   Cell culture, microinjection, and nuclear counterstaining: SH-SY5Y cells (ATCC, USA) were grown in proliferation medium (DMEM-F12 GlutaMAX™ + 10% heat inactivated FBS + 1% non-essential amino acids +10 mM HEPES buffer + 1% Penicillin/Streptomycin; Gibco®, Invitrogen, USA).	SH-SY5Y suggested: None
   Software and Algorithms
   Sentences	Resources
   AFM images were processed with the Scanning Probe Image Processor (SPIP	SPIP suggested: (SPIP, RRID:SCR_009410)
   Fibril morphology was analyzed using a custom fibril analysis Matlab script adapted from the FiberApp package.	Matlab suggested: (MATLAB, RRID:SC…

   SciScore for 10.1101/2021.04.12.439549: (What is this?)

   Please note, not all rigor criteria are appropriate for all manuscripts.

   Table 1: Rigor

   NIH rigor criteria are not applicable to paper type.

   Table 2: Resources

   Experimental Models: Cell Lines
   Sentences	Resources
   Cell culture, microinjection, and nuclear counterstaining: SH-SY5Y cells (ATCC, USA) were grown in proliferation medium (DMEM-F12 GlutaMAX™ + 10% heat inactivated FBS + 1% non-essential amino acids +10 mM HEPES buffer + 1% Penicillin/Streptomycin; Gibco®, Invitrogen, USA).	SH-SY5Y suggested: None
   Software and Algorithms
   Sentences	Resources
   AFM images were processed with the Scanning Probe Image Processor (SPIP	SPIP suggested: (SPIP, RRID:SCR_009410)
   Fibril morphology was analyzed using a custom fibril analysis Matlab script adapted from the FiberApp package.	Matlab suggested: (MATLAB, RRID:SCR_001622) FiberApp suggested: (FiberApp, RRID:SCR_015826)

   ---

   Results from OddPub: We did not detect open data. We also did not detect open code. Researchers are encouraged to share open data when possible (see Nature blog).

   ---

   Results from LimitationRecognizer: An explicit section about the limitations of the techniques employed in this study was not found. We encourage authors to address study limitations.

   ---

   Results from TrialIdentifier: No clinical trial numbers were referenced.

   ---

   Results from Barzooka: We did not find any issues relating to the usage of bar graphs.

   ---

   Results from JetFighter: We did not find any issues relating to colormaps.

   ---

   Results from rtransparent:

   • Thank you for including a conflict of interest statement. Authors are encouraged to include this statement when submitting to a journal.
   • No funding statement was detected.
   • No protocol registration statement was detected.

   ---

   Read the original source
3. 

   Version published to 10.1101/2021.04.12.439549v1 on bioRxiv

   Apr 12, 2021