Rational Design and Optimization of a Potent IDO1 Proteolysis Targeting Chimera (PROTAC)

  1. Paige J. Monsen
  2. Prashant V. Bommi
  3. Arabela A. Grigorescu
  4. Kristen L. Lauing
  5. Yingyu Mao
  6. Payton Berardi
  7. Lijie Zhai
  8. Oluwatomilayo Ojo
  9. Manon Penco-Campillo
  10. Taylor Koch
  11. Michael Egozi
  12. Sonam Jha
  13. Sara F. Dunne
  14. Hong Jiang
  15. Guiqin Song
  16. Fang Zhang
  17. Steven Kregel
  18. Ali Vaziri-Gohar
  19. Sean W. Fanning
  20. Pilar Sanchez-Gomez
  21. Jacob M. Allen
  22. Bakhtiar Yamini
  23. Rimas V. Lukas
  24. Derek A. Wainwright
  25. Gary E. Schiltz
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  1. Version published to 10.1021/acs.jmedchem.5c00026
  2. Version published to 10.1101/2025.01.07.631731 on bioRxiv