Seroprevalence and risk factors of exposure to COVID-19 in homeless people in Paris, France: a cross-sectional study

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Abstract

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  1. SciScore for 10.1101/2020.10.07.20207795: (What is this?)

    Please note, not all rigor criteria are appropriate for all manuscripts.

    Table 1: Rigor

    NIH rigor criteria are not applicable to paper type.

    Table 2: Resources

    Antibodies
    SentencesResources
    A target sample size of 791 individuals was based on the hypothesis that the seroprevalence of anti-SARS-COV2 antibodies among populations living in insecure conditions served by MSF would be two to three fold higher than the modelled estimate for the general population in IDF of 12% (3).
    anti-SARS-COV2
    suggested: None
    The LuLISA technique can be used to assess the incidence of all the antibodies involved in a viral infection response (IgA, IgM and, as used here, IgG) and is considered highly sensitive.
    IgA, IgM
    suggested: None
    For example, an individual sharing the room with no other person (level 1), the kitchen and sanitary facilities with 1 other person (each of level 2), and who reported on average 1 close contact per day (level 2) would be assigned an indicator value of seven – representing the medium crowding category. 3. Sensitivity analysis – seroprevalence estimates by type of sites: We performed a sensitivity analysis of seroprevalence estimates taking uncertainty about diagnostic test performances into account as described in “Seroprevalence of anti-SARS-CoV-2 IgG antibodies in Geneva, Switzerland (SEROCoV-POP): a population-based study.
    anti-SARS-CoV-2 IgG
    suggested: None
    Software and Algorithms
    SentencesResources
    The data were analysed using Stata V.15 software (StataCorp. 2017. College Station, TX) and R (R 3.6.2).
    StataCorp
    suggested: (Stata, RRID:SCR_012763)

    Results from OddPub: We did not detect open data. We also did not detect open code. Researchers are encouraged to share open data when possible (see Nature blog).


    Results from LimitationRecognizer: We detected the following sentences addressing limitations in the study:
    Our study has several limitations. First, due to the cross-sectional study design, it is not possible to determine when participants became seropositive. In relation to the sampling strategy, the selection of the study sites was not random: the locations were determined by MSF’s operational activities during the first wave of the pandemic in Ile-de-France and other considerations including security constraints and agreement of the sites to give the survey team access. Therefore, our results cannot be extrapolated to other populations living in similarly precarious situations in France or elsewhere. The selection of participants within the study sites could be potentially subject to bias despite the efforts made by the study team to obtain a representative sample; depending on the site, up to one third of those originally selected for inclusion were replaced by another participant. If those replacing the initially selected individuals had a higher risk of exposure, due to, for example, spending more t more time within the place of residence, this could have led to an overestimate of prevalence in the study population. Conversely, refusal to participate could have been higher among those who had previously tested positive, which would bias the seroprevalence estimate in the opposite direction. In addition to possible selection bias, information bias may have affected the measurement of other self-reported exposures,, including living conditions before and during confinement, CO...

    Results from TrialIdentifier: No clinical trial numbers were referenced.


    Results from Barzooka: We did not find any issues relating to the usage of bar graphs.


    Results from JetFighter: We did not find any issues relating to colormaps.


    Results from rtransparent:
    • Thank you for including a conflict of interest statement. Authors are encouraged to include this statement when submitting to a journal.
    • Thank you for including a funding statement. Authors are encouraged to include this statement when submitting to a journal.
    • No protocol registration statement was detected.

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