Effects of non-pharmaceutical interventions on COVID-19 cases, deaths, and demand for hospital services in the UK: a modelling study

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Abstract

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  1. SciScore for 10.1101/2020.04.01.20049908: (What is this?)

    Please note, not all rigor criteria are appropriate for all manuscripts.

    Table 1: Rigor

    NIH rigor criteria are not applicable to paper type.

    Table 2: Resources

    No key resources detected.


    Results from OddPub: Thank you for sharing your code and data.


    Results from LimitationRecognizer: We detected the following sentences addressing limitations in the study:
    The model presented here is subject to several limitations. Because the model does not explicitly structure individuals by household, we are unable to evaluate the impact of measures based on household contacts, e.g. household quarantine, i.e., where all members of a household with a suspected COVID-19 case remain in isolation. Such contact-targeted measures could increase the impact of a package of interventions by limiting spread in the community. However, the presence of asymptomatic infections [23] means that isolation based on symptomatic case identification would be unlikely to fully prevent ongoing transmission. We also do not include individual level variation in transmission (i.e. ‘superspreading events’, [24]). There are several examples of such events for COVID-19 [25], and individual-level variation is likely important in influencing the success of control measures in the very early stages of an outbreak [5]. However, as outbreaks of directly-transmitted infections become larger, the population-level dynamics will predominantly be driven by the average mixing pattern between key epidemiological groups, particularly between different ages [11,26]. We therefore used a stochastic model implementation to capture variation in these population-level dynamics. We also assumed that subclinically-infected individuals were 50% as infectious as clinical cases. A study of 2,147 close contacts in Ningbo, China estimated that the mean onward transmission from asymptomatic infec...

    Results from TrialIdentifier: No clinical trial numbers were referenced.


    Results from Barzooka: We did not find any issues relating to the usage of bar graphs.


    Results from JetFighter: We did not find any issues relating to colormaps.


    Results from rtransparent:
    • Thank you for including a conflict of interest statement. Authors are encouraged to include this statement when submitting to a journal.
    • Thank you for including a funding statement. Authors are encouraged to include this statement when submitting to a journal.
    • No protocol registration statement was detected.

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