Physical, cognitive, and mental health impacts of COVID-19 after hospitalisation (PHOSP-COVID): a UK multicentre, prospective cohort study
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SciScore for 10.1101/2021.03.22.21254057: (What is this?)
Please note, not all rigor criteria are appropriate for all manuscripts.
Table 1: Rigor
Institutional Review Board Statement Consent: Written informed consent was obtained from all study participants.
IRB: The study was approved by the Leeds West Research Ethics Committee (20/YH/0225) and is registered on the ISRCTN Registry (ISRCTN10980107).Randomization not detected. Blinding not detected. Power Analysis not detected. Sex as a biological variable not detected. Table 2: Resources
Software and Algorithms Sentences Resources Model derivation and validation was performed in imputed datasets, with Rubin’s rules28 used to combine results. Rubin’ssuggested: NoneUnsupervised clustering of patient symptom questionnaire, physical performance and cognitive assessment data (Dyspnoea-12, FACIT, GAD-7, … SciScore for 10.1101/2021.03.22.21254057: (What is this?)
Please note, not all rigor criteria are appropriate for all manuscripts.
Table 1: Rigor
Institutional Review Board Statement Consent: Written informed consent was obtained from all study participants.
IRB: The study was approved by the Leeds West Research Ethics Committee (20/YH/0225) and is registered on the ISRCTN Registry (ISRCTN10980107).Randomization not detected. Blinding not detected. Power Analysis not detected. Sex as a biological variable not detected. Table 2: Resources
Software and Algorithms Sentences Resources Model derivation and validation was performed in imputed datasets, with Rubin’s rules28 used to combine results. Rubin’ssuggested: NoneUnsupervised clustering of patient symptom questionnaire, physical performance and cognitive assessment data (Dyspnoea-12, FACIT, GAD-7, PHQ-9, PCL-5, SPPB and MoCA as continuous variables) was performed using the clustering large applications (CLARA) k-medoids approach. MoCAsuggested: (MOCA, RRID:SCR_010638)Results from OddPub: We did not detect open data. We also did not detect open code. Researchers are encouraged to share open data when possible (see Nature blog).
Results from LimitationRecognizer: We detected the following sentences addressing limitations in the study:This study has a number of limitations. The patients represent a small sample of the total number of patients discharged from hospital following COVID-19 infection in the UK. The study population is younger than the whole population in the UK that survived hospitalisation for COVID-19 infection40 and only included those able to attend clinic visits and undertake the study procedures. This acquisition bias might under-represent the most severely affected patients but conversely those patients with ongoing symptoms might have been more willing to participate. The patient-reported outcomes, physical and biological tests assessed cross-sectionally does not allow for the clear differentiation between the contribution from premorbid disease versus emergent impaired health status and symptoms. Further analysis of the trajectory of recovery and linkage to primary and secondary health records within PHOSP-COVID will enable further discrimination. Notwithstanding this limitation, the magnitude of burden of physical and mental health is substantial in this group. Our definition for recovery in this report is a subjective definition based on patient perception and will fail to identify pathological changes that have not yet led to clinical expression, but might become overt in later follow-up. However, patient-perceived recovery did correspond well to the overall burden of disease identified in the recovery phenotypes. Further comparisons are also required with recovery following acute r...
Results from TrialIdentifier: We found the following clinical trial numbers in your paper:
Identifier Status Title ISRCTN10980107 NA NA Results from Barzooka: We did not find any issues relating to the usage of bar graphs.
Results from JetFighter: We did not find any issues relating to colormaps.
Results from rtransparent:- Thank you for including a conflict of interest statement. Authors are encouraged to include this statement when submitting to a journal.
- Thank you for including a funding statement. Authors are encouraged to include this statement when submitting to a journal.
- Thank you for including a protocol registration statement.
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